(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID
![(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Structure](CAS/GIF/157604-55-2.gif)
- CAS No.
- 157604-55-2
- Chemical Name:
- (S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID
- Synonyms
- (S)-SP5114;(S)-SNAP 5114;SNAP 5114 (S)-;(S)-SNAP-5114 >=98% (HPLC), solid;(S)SNAP5114,(S)-SNAP-5114,(S) SNAP5114;S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIP;(S)-1-(2-(Tris(4-methoxyphenyl)methoxy)ethyl)piperidine-3-carboxylic acid;1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-(S)-3-PIPERIDINECARBOXYLIC ACID;(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID;3-Piperidinecarboxylic acid, 1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-, (3S)-
- CBNumber:
- CB8271118
- Molecular Formula:
- C30H35NO6
- Molecular Weight:
- 505.6
- MDL Number:
- MFCD06411702
- MOL File:
- 157604-55-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S1069 | (S)-SNAP-5114 ≥98% (HPLC), solid | 157604-55-2 | 5mg | $146 | 2024-03-01 | Buy |
| Sigma-Aldrich | S1069 | (S)-SNAP-5114 ≥98% (HPLC), solid | 157604-55-2 | 25mg | $522 | 2024-03-01 | Buy |
| Tocris | 1561 | (S)-SNAP5114 ≥98%(HPLC) | 157604-55-2 | 50 | $876 | 2021-12-16 | Buy |
| Tocris | 1561 | (S)-SNAP5114 ≥98%(HPLC) | 157604-55-2 | 10 | $216 | 2021-12-16 | Buy |
| TRC | S590253 | (S)-SNAP5114 | 157604-55-2 | 10mg | $195 | 2021-12-16 | Buy |
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
(S)-SNAP 5114 is a GABA, GAT3 inhibitor.
Biological Activity
GABA transport inhibitor, showing selectivity for GAT-3 and GAT-2 (IC 50 values are 5, 21 and 388 μ M for hGAT-3, rGAT-2 and hGAT-1 respectively). Increases thalamic GABA levels and is an anticonvulsant following systemic administration in vivo .
storage
Store at -20°C
References
[1]. borden la, dhar tg, smith ke, et al. cloning of the human homologue of the gaba transporter gat-3 and identification of a novel inhibitor with selectivity for this site. receptors channels, 1994, 2(3): 207-213.
[2]. pabel j, faust m, prehn c, et al. development of an (s)-1-{2-[tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(s)-snap-5114] carba analogue inhibitor for murine γ-aminobutyric acid transporter type 4. chemmedchem, 2012, 7(7): 1245-1255.
[3]. dalby no. gaba-level increasing and anticonvulsant effects of three different gaba uptake inhibitors. neuropharmacology, 2000, 39(12): 2399-2407.
[4]. kataoka k, hara k, haranishi y, et al. the antinociceptive effect of snap5114, a gamma-aminobutyric acid transporter-3 inhibitor, in rat experimental pain models. anesth analg, 2013, 116(5): 1162-1169.
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2988 | 58 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4997 | 55 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |