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NS 1619

NS 1619 structure

CAS No.: 153587-01-0

Chemical Name:: NS 1619

Synonyms: NS 161;NS 1619;NS1619;NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-

CBNumber:: CB8359809

Molecular Formula:: C15H8F6N2O2

Molecular Weight:: 362.23

MDL Number:: MFCD00928190

MOL File:: 153587-01-0.mol

Last updated:2024-11-19 20:33:22

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NS 1619 Properties

Density	1.563±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka	8.32±0.48(Predicted)
form	solid
color	white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3

NS 1619 price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	N170	NS 1619 powder	153587-01-0	5mg	$180	2024-03-01	Buy
Sigma-Aldrich	N170	NS 1619 powder	153587-01-0	25mg	$645	2024-03-01	Buy
Cayman Chemical	18876	NS 1619 ≥98%	153587-01-0	1mg	$37	2024-03-01	Buy
Cayman Chemical	18876	NS 1619 ≥98%	153587-01-0	5mg	$81	2024-03-01	Buy
Cayman Chemical	18876	NS 1619 ≥98%	153587-01-0	10mg	$142	2024-03-01	Buy

Product number	Packaging	Price	Buy
N170	5mg	$180	Buy
N170	25mg	$645	Buy
18876	1mg	$37	Buy
18876	5mg	$81	Buy
18876	10mg	$142	Buy

NS 1619 Chemical Properties,Uses,Production

Uses

NS 1619 is a large conductance calcium-activated potassium channels (BKCa) activator and has been shown to induce precondition in the heart.

Definition

ChEBI: A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It i an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Biochem/physiol Actions

NS 1619 is a selective large conductance Ca2+-activated K+-channel activator. The compound is known for its vasodilating and anti-proliferative properties. It is studied that NS 1619 can protect cardiac muscle against ischemia and reperfusion injury.

storage

+4°C

NS 1619 Preparation Products And Raw materials

Raw materials

Preparation Products

NS 1619 Suppliers

Global( 98)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
RR Scientific LLC	+86-13917743231	sales@rrscientific.com	United States	878	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38632	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
InvivoChem	58
RR Scientific LLC	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58

View Lastest Price from NS 1619 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	NS-1619 153587-01-0	US $31.00-72.00 / mg		98.28%	10g	TargetMol Chemicals Inc.
	2020-01-14	NS 1619 153587-01-0	US $9.80 / KG	1g	≥99%	100kg	Career Henan Chemical Co

NS-1619
153587-01-0
US $31.00-72.00 / mg
98.28%
TargetMol Chemicals Inc.

NS 1619
153587-01-0
US $9.80 / KG
≥99%
Career Henan Chemical Co

NS 1619 Spectrum

NS 1619(153587-01-0)¹HNMR

153587-01-0(NS 1619)Related Search:

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5-HYDROXYDECANOIC ACID SODIUM SALT CLOFILIUM TOSYLATE Gabapentin-lactam PAXILLINE 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole

NS 11394 Selexipag N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE

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NS 1619 NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN 1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE 1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one 1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b NS1619;NS 1619 NS 161 2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)- 1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one 1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one 1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol 153587-01-0 C15H8F6N2O2 Monovalent Ion Channels Ion Channels Voltage-gated Ion Channels Potassium Channel Modulators Cell Signaling and Neuroscience Cell Biology BioChemical API