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Meisoindigo

CAS No.
97207-47-1
Chemical Name:
Meisoindigo
Synonyms
CS-1454;Natura-α;Dian III;Natura-α;MEISOINDIGO;3'-digallate;Theaflavine-3;Meisoindigo, >96%;Methylisoindigotin;Meisoindigo, >=98%
CBNumber:
CB8394558
Molecular Formula:
C17H12N2O2
Molecular Weight:
276.29
MDL Number:
MFCD05988503
MOL File:
97207-47-1.mol
Last updated:2024-11-20 11:41:24

Meisoindigo Properties

Melting point 236-237°C
Boiling point 482.0±45.0 °C(Predicted)
Density 1.381±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility insoluble in H2O; insoluble in EtOH; ≥25.85 mg/mL in DMSO with ultrasonic
form powder to crystal
pka 11.62±0.20(Predicted)
color Orange to Brown to Dark red
FDA UNII 92UIP6405R

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933.79.1500
NFPA 704
0
2 0

Meisoindigo price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M3082 Meisoindigo >98.0%(HPLC) 97207-47-1 25mg $150 2024-03-01 Buy
TCI Chemical M3082 Meisoindigo >98.0%(HPLC) 97207-47-1 100mg $410 2024-03-01 Buy
Cayman Chemical 18007 Meisoindigo ≥95% 97207-47-1 500μg $44 2024-03-01 Buy
Cayman Chemical 18007 Meisoindigo ≥95% 97207-47-1 1mg $78 2024-03-01 Buy
Cayman Chemical 18007 Meisoindigo ≥95% 97207-47-1 5mg $341 2024-03-01 Buy
Product number Packaging Price Buy
M3082 25mg $150 Buy
M3082 100mg $410 Buy
18007 500μg $44 Buy
18007 1mg $78 Buy
18007 5mg $341 Buy

Meisoindigo Chemical Properties,Uses,Production

Description

Meisoindigo is a derivative of indirubin that has anticancer activity. It inhibits the growth of NB4, HL-60, and U937 leukemia and primary acute myeloid leukemia (AML) cells when used at concentrations of 5 and 10 μM. It also halts the cell cycle at the G0/G1 phase and induces apoptosis in leukemia cell lines and primary AML cells, induces myeloid differentiation, and potentiates the effects of cytarabine and idarubicin . Meisoindigo (10 μM) also induces apoptosis, decreases adherence, and decreases the expression of vascular cell adhesion molecule-1 (VCAM-1) in ECV304 human vein endothelial cells. Meisoindigo (50-150 mg/kg per day) decreases spleen size in an HL-60 mouse xenograft model of AML in a dose-dependent manner.

Chemical Properties

mp 236-237°C

Uses

Meisoindigo is a 5-HT3 receptor antagonist prevents acute nausea and vomiting associated with emetogenic cancer chemotherapy

Uses

Meisoindigo shows strong anti-proliferation effect against gemcitabine-resistant Pancreatic ductal adenocarcinoma (PDACs).

References

[1] lee cc, lin cp, lee yl, wang gc, cheng yc, liu he. meisoindigo is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia. leuk lymphoma. 2010 may;51(5):897-905.

Meisoindigo Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 142)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 22784 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
Labnetwork lnc.
+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58

View Lastest Price from Meisoindigo manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Meisoindigo pictures 2024-11-19 Meisoindigo
97207-47-1
US $64.00-178.00 / mg 98.19% 10g TargetMol Chemicals Inc.
Meisoindigo USP/EP/BP pictures 2021-07-02 Meisoindigo USP/EP/BP
97207-47-1
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Meisoindigo pictures 2020-04-30 Meisoindigo
97207-47-1
US $0.00-0.00 / Kg 1KG 99.0%+ 800 tons Shaanxi Dideu Medichem Co. Ltd
  • Meisoindigo pictures
  • Meisoindigo
    97207-47-1
  • US $64.00-178.00 / mg
  • 98.19%
  • TargetMol Chemicals Inc.
  • Meisoindigo pictures
  • Meisoindigo
    97207-47-1
  • US $0.00-0.00 / Kg
  • 99.0%+
  • Shaanxi Dideu Medichem Co. Ltd

Meisoindigo Spectrum

1-METHYL-3,3'-BIINDOLE-2,2'(1H,1'H)-DIONE 3-(1,2-dihydro-2-oxo-3h-indol-3-ylidene)-1,3-dihydro-1-methyl-2h-indol-2-one MEISOINDIGO N-methylisoindigotin Dian III Methylisoindigotin Natura-α Meisoindigo 3-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)-1,3-dihydro-1-methyl-2H-indol-2-one Meisoindigo, >=98% Methylisoindigotin Meisoindigo Meisoindigo, >96% CS-1454 Meisoindigo(Natura- DIAN III; N-METHYLISOINDIGOTIN; NATURA-Α 2H-Indol-2-one, 3-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)-1,3-dihydro-1-methyl- (3E)-1-methyl-3-(2-oxo-1H-indol-3-ylidene)indol-2-one Meisoindigo USP/EP/BP 1-methyl-3-(2-oxo-1H-indol-3-ylidene)indol-2-one Natura-α 3'-digallate Theaflavine-3 (E)-1-methyl-[3,3'-biindolinylidene]-2,2'-dione 1-Methyl-[3,3'-biindolinylidene]-2,2'-dione 1-Methyl-[3,3'-biindolinylidene]-2,2'-dione 97207-47-1 Inhibitors