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ChemicalBook >> CAS DataBase List >>4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile

4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile

4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Structure
4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile structure
CAS No.
939431-68-2
Chemical Name:
4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile
Synonyms
Etravirine Impurity 12;4-[[6-amino-2-(4-cyanoanilino)-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile;4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile;4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile;Benzonitrile, 4-[[6-amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-
CBNumber:
CB84195249
Molecular Formula:
C20H16N6O
Molecular Weight:
356.38
MDL Number:
MFCD17012694
MOL File:
939431-68-2.mol
Last updated:2022-12-21 16:56:50
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4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Properties

Melting point 284.5-287 °C
Boiling point 632.1±65.0 °C
FDA UNII X6ZC3L4U55

4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Chemical Properties,Uses,Production

Uses

4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile is an impurity of Etravirine (E937000), which is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection. It can be used as a novel HIV-1 NNRTIs by using its hydrophobic channel and tolerant regions of NNIBP. It can also be used to synthesize etravirine, a non-nucleoside reverse transcriptase inhibitor.

4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15386 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Shanghai Massive Chemical Technology Co., Ltd. +86-021-34943721 +86-18616806816 info@massivechem.com China 89 55
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016; 18162595016 3287908757@qq.com China 9117 58
JIANGSU BSECHEM CHEMICAL TECHNOLOGY Co., Ltd 15651337098 15651337098@163.com China 3010 58
Supplier Advantage
AFINE CHEMICALS LIMITED 		58
Amadis Chemical Company Limited 		58
Shanghai Massive Chemical Technology Co., Ltd. 55
Meng Cheng Technology (Shanghai) Co., LTD 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 58
JIANGSU BSECHEM CHEMICAL TECHNOLOGY Co., Ltd 58
4-({6-amino-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile Etravirine Impurity 12 4-[[6-amino-2-(4-cyanoanilino)-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile Benzonitrile, 4-[[6-amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl- 4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile 939431-68-2