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proTAME

CAS No.
1362911-19-0
Chemical Name:
proTAME
Synonyms
proTAME;pro-Tosyl-L-Arginine Methyl Ester;(2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoicacid,methylester;10,12-Dioxa-6,8-diazatetradec-6-enoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-, methyl ester, (2S)-
CBNumber:
CB84666792
Molecular Formula:
C34H38N4O12S
Molecular Weight:
726.75
MDL Number:
MFCD32671680
MOL File:
1362911-19-0.mol
Last updated:2024-07-02 08:55:36

proTAME Properties

Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: Soluble
pka 7.05±0.46(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Signal word  Warning
Hazard statements  H227
Precautionary statements  P210-P280-P370+P378-P403+P235-P501
NFPA 704
2
0 0

proTAME price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25835 proTAME ≥90% 1362911-19-0 1mg $305 2024-03-01 Buy
AK Scientific 1830DN Methyl(2S)-5-[bis[(2-phenylacetyl)oxymethoxycarbonylamino]methylideneamino]-2-[(4-methylphenyl)sulfonylamino]pentanoate 1362911-19-0 1mg $565 2021-12-16 Buy
Product number Packaging Price Buy
25835 1mg $305 Buy
1830DN 1mg $565 Buy

proTAME Chemical Properties,Uses,Production

Description

ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significantly increase cell death in Multiple Myeloma (MM) cell lines and primary cells, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.

proTAME Preparation Products And Raw materials

Raw materials

Preparation Products

proTAME Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 922 64
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613 sales@chemrenpharm.com China 3574 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
SINO High Goal Chemical Technology Co., Ltd. 021-57646680 18306277365 guoxin@chembiobanksh.com China 2287 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2497 58
proTAME pro-Tosyl-L-Arginine Methyl Ester 10,12-Dioxa-6,8-diazatetradec-6-enoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-, methyl ester, (2S)- (2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoicacid,methylester 1362911-19-0