C18 Globotriaosylceramide (d18:1/18:0)
- CAS No.
- 69283-33-6
- Chemical Name:
- C18 Globotriaosylceramide (d18:1/18:0)
- Synonyms
- Octadecanoyl-ceramide trihexoside;N-Octadecanoyl-ceramide trihexoside;C18 Globotriaosylceramide (d18:1/18:0);Octadecanamide, N-[(1S,2R,3E)-1-[[(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-
- CBNumber:
- CB84666974
- Molecular Formula:
- C54H101NO18
- Molecular Weight:
- 1052.37564
- MDL Number:
- MOL File:
- 69283-33-6.mol
C18 Globotriaosylceramide (d18:1/18:0) price More Price(1)
C18 Globotriaosylceramide (d18:1/18:0) Chemical Properties,Uses,Production
Description
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. C18 globotriaosylceramide also accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. [Matreya, LLC. Catalog No. 1529]
Definition
ChEBI: Alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1/18:0) is a glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl as the glycotriaosyl component attached to the Cer(d18:1/18:0). It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid.
C18 Globotriaosylceramide (d18:1/18:0) Preparation Products And Raw materials
Raw materials
Preparation Products
C18 Globotriaosylceramide (d18:1/18:0) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
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