ChemicalBook >> CAS DataBase List >>2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
- CAS No.
- 657408-07-6
- Chemical Name:
- 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
- Synonyms
- 98% SPhos;Dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane;dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane;6´NS-PHOS;SPhos 97%;SPhos, >=98%;REF DUPL: S-PHOS;-diMethoxybiphenyl;S-Phos, ChemDose(TM) tablets
- CBNumber:
- CB8634850
- Molecular Formula:
- C26H35O2P
- Molecular Weight:
- 410.53
- MDL Number:
- MFCD05861611
- MOL File:
- 657408-07-6.mol
- MSDS File:
- SDS
Last updated:2024-08-21 22:41:43
| Melting point | 164-166°C |
|---|---|
| Boiling point | 513.3±40.0 °C(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Chloroform |
| form | crystal |
| color | white |
| Sensitive | Air Sensitive |
| InChIKey | VNFWTIYUKDMAOP-UHFFFAOYSA-N |
| FDA UNII | XI1MQ32186 |
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 901906 | SPhos 95% | 657408-07-6 | 1G | $31.44 | 2024-03-01 | Buy |
| Sigma-Aldrich | 901906 | SPhos 95% | 657408-07-6 | 5G | $143 | 2024-03-01 | Buy |
| Sigma-Aldrich | 901906 | SPhos 95% | 657408-07-6 | 25G | $270.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 932191 | SPhos ChemBeads | 657408-07-6 | 1g | $287 | 2024-03-01 | Buy |
| Sigma-Aldrich | 901906 | SPhos 95% | 657408-07-6 | 250G | $736 | 2024-03-01 | Buy |
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Chemical Properties,Uses,Production
Uses
SPhos [2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.
SPhos may be used as a ligand in the following processes:
• Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between Boc-protected aminomethyltrifluoroborate and aryl chlorides or hetaryl chlorides to form the corresponding aminomethylarenes.• Palladium catalyzed Suzuki-Miyaura cross-coupling reaction between 4-methyl-substituted piperidinylzinc reagent and different aryl or heteroaryl iodides to form various substituted piperidines.• Intramolecular Suzuki-Miyaura coupling to form the 18-membered macrocyclic ring during the multi-step synthesis of riccardin C.
Utilized in conjunction with palladium to form a highly active catalyst for C-N bond formation.
Highly universal ligand for Suzuki-Miyaura coupling; aryl chlorides, hindered biaryls, heterobiaryls.
Reactions
- Ligand/palladium catalyst for general Suzuki-Miyaura cross-coupling reactions.
- Ligand/palladium catalyst for the Suzuki-Miyaura coupling of aryltrifluoroborates with aryl chlorides.
- Ligand/palladium catalyst for the Suzuki-Miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters.
- Ligand/palladium catalyst for the Kumada-Corriu cross-coupling reaction.
- Ligand/palladium catalyst for the borylation of aryl halides with pinacol borane.
- Suzuki couplings involving amino acids. Synthesis of biaryl derivatives of 4-hydroxyphenyl glycine, tyrosine and tryptophan.
- Synthesis of substituted adamantylzinc reagents using Mg-insertion in the presence of zinc chloride.
- Highly efficient catalyst for the palladium-catalyzed Suzuki-Miyura reaction of heteroaryl halides and heteroaryl boronic acids
- and esters.
Chemical Properties
White solid
Uses
suzuki reaction
Uses
S-Phos is a catalyst that is used in the preparation of thiadiazoles as DGAT1 inhibitors with potential in metabolic diseases treatment.
General Description
SPhos [2-Dicyclohexylphosphino-2′, 6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.
Synthesis of 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl from 2-Bromochlorobenzene and 1,3-Dimethoxybenzene and Dicyclohexylchlorophosphine
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Preparation Products And Raw materials
Global( 401)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XINXIANG RUNYU MATERIAL CO., LTD. | +86-13592593621; +8613592593621 | sales@runvmat.com | China | 439 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18779 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9214 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
View Lastest Price from 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-21 | 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
657408-07-6
|
US $0.00 / Kg/Drum | 1KG | 99% | 200mt | Jinan Finer Chemical Co., Ltd | |
 |
2024-10-11 | SPHOS
657408-07-6
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-07-11 | SPhos
657408-07-6
|
US $1290.00 / Kg | 1Kg | 98 | 500 Kg | R&D Scientific Inc. |
-
- 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
657408-07-6
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
-
- SPHOS
657408-07-6
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- SPhos
657408-07-6
- US $1290.00 / Kg
- 98
- R&D Scientific Inc.
657408-07-6(2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl)Related Search:
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2-DICYCLOHEXYLPHOSPHINO-2',6'-DIISOPROPOXYBIPHENYL
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dicyclohexyl({2-[(2,6-dimethoxyphenyl)methyl]phenyl}methyl)phosphane
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Phosphine,dicyclohexyl(2',6'-dimethoxy[1,1'-biphenyl]-2-yl)-
SPhos, >=98%
2-Dicyclohexylphosphino-2’,6’-dimethoxy-1,1’-biphenyl (S-Phos)
2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHOXY-1,1'-BIPHENYL, MIN. 98% S-PHOS
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl, min. 98%
S-Phos impregnated tablets, ChemDose(R), S-Phos tablets, 2-Dicyclohexylphosphino-2μ,6μ-dimethoxybiphenyl impregnated tablets
S-Phos, ChemDose(R) tablets
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
6´
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl, 98+%
REF DUPL: S-PHOS
2-Dicyclohexylphosphino-2',6'-dimethoxybipheny
Dicyclohexyl(2',6'-dimethoxybiphenyl-2-yl)phosphine
2-Dicyclohexylphosphino-2´
-diMethoxybiphenyl
S-PHOS, 2-Dicyclohexylphosphino-2,6-di-Methyloxy-1,1-biphenyl
Dicyclohexyl(2',6'-diMethoxy-[1,1'-biphenyl
S-phos, 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl Sphos
Sphos / 2-Dicyclohexylphosphino-2'',6''-dimethoxy-1,1''-biphenyl
2-(Dicyclohexylphosphanyl)-2',6'-dimethoxybiphenyl 98%
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl 657408-07-6 250g
-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
2-DICYLOHEXYLPHOSPHINO-2,6-DIMETHOXYBIPHENYL
phosphino-2’,6’-dimethoxybiphenyL
phosphino-2',6'-dimethoxy-1,1'-biphenyL
NS-PHOS
S-Phos, ChemDose(TM) tablets
2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl,min.98%
2-Dicyclohexyphosphino-2'6'-dimethoxy-1,1'-biphenyl (Sphos)
S-Phos (2-Dicyclohexylphosphino-2,6-Dimethoxybiphenyl) extrapure, 98%
98% SPhos
Dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane
dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane
Dicyclohexyl(2',6'-dimethoxybiphenyl-2-yl)phosphine(S-PHOS)
2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHOXY-1,1'-BIPHENYL
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl(Sphos)
Dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine
dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane
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2-Dicyclohexylphosphino-2'',6''-dimethoxybiphenyl
Bromo(tri-tert-butylphosphine)palladium()dimer
657408-07-6