ChemicalBook >> CAS DataBase List >>X-PHOS
X-PHOS
- CAS No.
- 564483-18-7
- Chemical Name:
- X-PHOS
- Synonyms
- 5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE;2-Dicyclohexylphosphino-2;dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane;X-PH0S;dicyclohexyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;X-PHOS;98% XPhos;XPhos 97%;2-(DicycL;XPhos, >=98%
- CBNumber:
- CB3357527
- Molecular Formula:
- C33H49P
- Molecular Weight:
- 476.72
- MDL Number:
- MFCD04117682
- MOL File:
- 564483-18-7.mol
- MSDS File:
- SDS
Last updated:2024-08-21 22:41:43
Melting point | 187-190 °C(lit.) |
---|---|
Boiling point | 569.8±50.0 °C(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Benzene (Slightly) |
form | Powder |
color | white |
Sensitive | Air Sensitive |
Stability | Air Sensitive |
InChIKey | UGOMMVLRQDMAQQ-UHFFFAOYSA-N |
CAS DataBase Reference | 564483-18-7(CAS DataBase Reference) |
FDA UNII | R271FU23T8 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H351 | |||||||||
Precautionary statements | P280 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 36/37/38-22-40 | |||||||||
Safety Statements | 37/39-26-36/37 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | No | |||||||||
HS Code | 29319090 | |||||||||
NFPA 704 |
|
X-PHOS price More Price(46)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 638064 | XPhos 97% | 564483-18-7 | 1g | $92.5 | 2024-03-01 | Buy |
Sigma-Aldrich | 638064 | XPhos 97% | 564483-18-7 | 5g | $171 | 2024-03-01 | Buy |
TCI Chemical | D5038 | 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl >98.0%(GC) | 564483-18-7 | 1g | $98 | 2024-03-01 | Buy |
TCI Chemical | D5038 | 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl >98.0%(GC) | 564483-18-7 | 5g | $288 | 2024-03-01 | Buy |
Strem Chemicals | 15-1149 | 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% XPhos | 564483-18-7 | 500mg | $33 | 2024-03-01 | Buy |
X-PHOS Chemical Properties,Uses,Production
Reaction
- Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates.
- Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling reaction and carbonyl enolate coupling.
- Ligand used for the chemoselective amination of aryl chlorides.
- Ligand used for the Pd-catalyzed borylation of aryl chlorides, for the formation of trifluoroborates.
- Ligand used for the Pd-catalyzed amination of vinyl halides and triflates.
- Ligand used for the Pd-catalyzed three-component synthesis of indoles.
- Ligand used for the Pt-catalyzed regioselective hydrosilylation of functionalized terminal arylalkynes.
- Ligand used for the Pd-catalyzed synthesis of carbazoles.
- Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling of aryl chloride and NHC-boranes.
- Ligand used for the direct arylation of picoline N-oxide.
- Ligand used for the Negishi coupling of 2-heterocyclic organozinc reagents.
- Catalyst for a phosphine-catalyzed Heine reaction.
- Ligand used for the palladium-catalyzed oxidative coupling of indoles and heteroarenes.
- Ligand used for the silver-catalyzed hydrogenation of aldehydes.
- Ligand used for the palladium-catalyzed cyanation of heterycyclic halides.
![Reactions of 564483-18-7_1](/NewsImg/2018-04-26/201842617492634047.jpg)
![Reactions of 564483-18-7_2](/NewsImg/2018-04-26/201842617493334843.jpg)
![Reactions of 564483-18-7_3](/NewsImg/2018-04-26/201842617494022476.jpg)
![Reactions of 564483-18-7_4](/NewsImg/2018-04-26/201842617494815219.jpg)
Chemical Properties
White crystalline powder
Uses
Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates. XPHOS is used as a regent in the synthesis of novel [1,2,4]triazolo[4,3-a]pyrazine derivatives as potential selective c-met inhibitors with improved pharmacokinetic properties.
Uses
suzuki reaction
General Description
This product has been enhanced for catalytic efficiency.
![21524-34-5](/CAS/GIF/21524-34-5.gif)
![16523-54-9](/CAS/GIF/16523-54-9.gif)
![583-53-9](/CAS/GIF/583-53-9.gif)
![564483-18-7](/CAS/GIF/564483-18-7.gif)
Synthesis of X-PHOS from 1-BROMO-2,4,6-TRIISOPROPYLBENZENE and Dicyclohexylchlorophosphine and 1,2-Dibromobenzene
X-PHOS Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Global( 487)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
XINXIANG RUNYU MATERIAL CO., LTD. | +86-13592593621; +8613592593621 | sales@runvmat.com | China | 432 | 58 |
Puyang Huicheng Electronic Materials Co., Ltd. | +86-0393-+86-0393-8910800 +8615839383373 | info@huichengchem.com | China | 524 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7034 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5828 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
Related articles
- X-PHOS: Properties and Applications as Catalyst
- X-PHOS, known for stability and reactivity, enhances palladium-catalyzed borylation with improved efficiency and selectivity, ....
- Jul 10,2024
- Activity of Silver-X-PHOS complex catalyst
- X-PHOS was first used at the beginning of the 21st century for the general amination and amidation of arenesulfonates and aryl....
- Oct 24,2019
View Lastest Price from X-PHOS manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2024-08-23 | 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
564483-18-7
|
US $32.00 / kg | 1kg | 99% | 200mt | Jinan Finer Chemical Co., Ltd | |
![]() |
2024-08-21 | X-PHOS
564483-18-7
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
![]() |
2024-08-07 | 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
564483-18-7
|
US $26.00-461.00 / g | 25g | 0.99 | 100kg | Shanghai UCHEM Inc. |
-
- 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
564483-18-7
- US $32.00 / kg
- 99%
- Jinan Finer Chemical Co., Ltd
-
- X-PHOS
564483-18-7
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
564483-18-7
- US $26.00-461.00 / g
- 0.99
- Shanghai UCHEM Inc.
564483-18-7(X-PHOS)Related Search:
5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE DIPOTASSIUM SALT
2-(Dicyclohexylphosphino)biphenyl
DI-N-PENTYLPHENYLPHOSPHINE
DIBUTYLPHENYLPHOSPHINE
2-(Dicyclohexylphosphino)-2'-methylbiphenyl
X-PHOS
Dicyclohexylphenylphosphine
5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE DISODIUM SALT
PNP-PHOS K
PNP-PHOS 2 CHX
1of4
X-PHOS
2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL
2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL
2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISOPROPYLBIPHENYL
2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, X-PHOS
2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98%X-Phos
2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl, 98+%
ChemDose(R), X-Phos impregnated tablets, 2-Dicyclohexylphosphino-2μ,4μ,6μ-triisopropylbiphenyl impregnated tablets
X-Phos, ChemDose(R) tablets
2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbip
2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,
2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl ,97%
2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl,XPhos
2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, 98+% X-PHOS
98% XPhos
2-(DicyclohexylphosphiNA)-2',4',6'-triisopropylbiphenyl
Dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphine
2,,4',6'-Diisopropyl-1,1'-biphenyl-2-yldicyclohexylphosphine
2-(Dicyclohexylphosphino)-2',4
2-(Dicyclohexylphosphanyl)-2',4',6'-tris(isopropyl)biphenyl
Dicyclohexyl[2',4',6'-tris(prop-2-yl)biphenyl-2-yl]phosphine, Dicyclohexyl[2',4',6'-tris(prop-2-yl)biphenyl-2-yl]phosphane, X-phos
Phosphine, dicyclohexyl[2',4',6'-tris(1-Methylethyl)[1,1'-biphenyl]-2-yl]-
XPhos 97%
2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL OR X-PHOS
(2-(2,4,6-triisopropylphenethyl)phenyl)dicyclohexylphosphine
X-PHOS,2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl
XPhos, >=98%
Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane
X-Phos, ChemDose? tablets
2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98%
dicyclohexyl[2',4',6'-tris(propan-2-yl)-[1,1'-biphenyl]-2-yl]phosphane
-biphenyl]-2-yl]phosphane
(2-(2,4,6-triisopropylphenethyl)phenyl)dicyclohexylphosphine(X-Phos)
2-(DicycL
phosphino)-2',4',6'-tri-i-propyL
Dicyclohexyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine
2-Dicyclohexylphosphino-2',4',6'-t
[2'-(methylamino)-[1,1'-biphenyl]-2-yl]palladio methanesulfonate
X-Phos, ChemDose(TM) tablets
-1,1'-biphenyL
2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98%
X-Phos ( 2-dicyclohexylphosphino-2’,4’,6’-triisopropylbiphenyl)
2-Dicyclohexylphosphino-2',4',6'-trisopropyl-1,1'-biphenyl(X-phos)
2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL,xphos
X-Phos (2-Dicyclohexylphosphino-2,4,6-Triisopropylbiphenyl) extrapure, 98%
5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE
2-Dicyclohexylphosphino-2
dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane
X-PH0S
dicyclohexyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane
2-Dicyclohexylphosphate-2 ', 4', 6 '- triisopropylbiphenyl
2-dicyclohexylphosphine 2',4',6' -triisopropyl biphenyl
Abemaciclib Impurity 31
Abemaciclib Impurity 39
2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl
2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL
XPhos(2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl)
2,,4',6'-Diisopropyl-1,1'-biphenyl-2-yldicyclohexylphosphine