ChemicalBook >> CAS DataBase List >>Bleomycin hydrochloride

Bleomycin hydrochloride

CAS No.
67763-87-5
Chemical Name:
Bleomycin hydrochloride
Synonyms
BleomycinHCl;bleomycinchlorhydrate;Suberic Acid Impurity 1;BLEOMYCIN HYDROCHLORIDE;BLEOMYCIN HYDROCHLORIDES;BleomycinA5/Pingyangmycin;BleoMycin A4A5 Hydrochloride;Bleomycin hydrochloride USP/EP/BP;Bleomycin, hydrochloride (9CI, ACI);Bleomycin hydrochlorideQ: What is Bleomycin hydrochloride Q: What is the CAS Number of Bleomycin hydrochloride Q: What is the storage condition of Bleomycin hydrochloride
CBNumber:
CB8770570
Molecular Formula:
C50H71N16O21S2R.x(HCl)
Molecular Weight:
0
MDL Number:
MFCD00211692
MOL File:
Mol file
Last updated:2024-11-19 23:02:33

Bleomycin hydrochloride Properties

storage temp. 4°C, protect from light
solubility DMSO: 125 mg/mL (86.15 mM)
form Solid
color White to light yellow
FDA UNII 7Z9O46JA4A

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

Bleomycin hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0131163 Bleomycin(hydrochloride) 98.81% 67763-87-5 10mg $168 2021-12-16 Buy
ChemScene CS-0131163 Bleomycin(hydrochloride) 98.81% 67763-87-5 50mg $672 2021-12-16 Buy
Product number Packaging Price Buy
CS-0131163 10mg $168 Buy
CS-0131163 50mg $672 Buy

Bleomycin hydrochloride Chemical Properties,Uses,Production

Originator

Bleomycin Hydrochloride,Nippon Kayaku, Co.,Japan

Manufacturing Process

To a medium having a composition of 6.4 % of millet jelly, 0.5 % of glucose, 3.5 % of soybean powder, 0.75 % of corn steep liquor, 0.3 % of sodium chloride, 0.1 % of potassium secondary phosphate, 0.05 % of zinc sulfate, 0.01 % of copper sulfate, 0.2 % of sodium nitrate and 0.01 % of Toho No. 1 (trade name for a surface active agent composed of polyoxyethylene manufactured by Toho Chemical Industry Co. Ltd., Japan) was added 3-aminopropyl- dimethylsulfonium bromide hydrobromate in a proportion of 0.4 mg/ml to adjust the pH of the medium to 6.5.
Each 100 ml of the thus treated medium was separately charged into a Sakaguchi flask and was then sterilized. Subsequently, Streptomyces verticillus (ATCC No. 15003) was inoculated in the medium and was cultured at 27°C for 8 days with stirring at 130 r.p.m. Thereafter, the culture liquors (4.5 L) were collected and filtered to obtain 3.0 L of a filtrate (potency 38.8 mg/ml, total potency 416.4 mg). This culture filtrate was passed through and adsorbed on a column packed with 200 ml of Amberlite IRC-50 and was washed with water and was eluted with 0.5 N hydrochloric acid. 1.0 L of the eluate was neutralized, was passed through and adsorbed on a column packed with 100 ml of active carbon, was washed and was then eluted by use of a 1:1 (by volume) mixture of acetone - 0.02 N aqueous hydrochloric acid solution, and fractions active to Mycobacterium 607 were collected and concentrated to dryness. The resulting residue was dissolved in 5 ml of an 80 % aqueous methanol solution and was charged into a column packed with 30 ml of neutral alumina, followed by elution with an 80 % aqueous methanol solution. Subsequently, bleomycin-containing fractions were collected and concentrated to dryness to obtain 195 mg of bleomycin hydrochloride (potency 650.7 mcg/mg, total potency 172 mg). The yield from the culture filtrate was 30.5 %.

Therapeutic Function

Antibiotic

Bleomycin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Bleomycin hydrochloride Suppliers

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 22787 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15352 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9414 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49978 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD
+86-0512-83500002 +8615195660023 sales@senfeida.com China 23046 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58

View Lastest Price from Bleomycin hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bleomycin hydrochloride pictures 2024-11-19 Bleomycin hydrochloride
67763-87-5
US $37.00-137.00 / mg 10g TargetMol Chemicals Inc.
Bleomycin hydrochloride USP/EP/BP pictures 2021-07-02 Bleomycin hydrochloride USP/EP/BP
67763-87-5
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Bleomycin hydrochloride pictures 2020-05-03 Bleomycin hydrochloride
67763-87-5
US $0.00-0.00 / Kg 1KG 99.0% 800 ton Shaanxi Dideu Medichem Co. Ltd

Bleomycin hydrochloride Spectrum

bleomycinchlorhydrate BleomycinA5/Pingyangmycin BleomycinHCl BLEOMYCIN HYDROCHLORIDES BleoMycin A4A5 Hydrochloride BLEOMYCIN HYDROCHLORIDE Bleomycin hydrochloride USP/EP/BP Bleomycin hydrochlorideQ: What is Bleomycin hydrochloride Q: What is the CAS Number of Bleomycin hydrochloride Q: What is the storage condition of Bleomycin hydrochloride Bleomycin, hydrochloride (9CI, ACI) Suberic Acid Impurity 1 67763-87-5 C50H71N16O21S2RxHCl