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PROTAC CRBN Degrader-1

PROTAC CRBN Degrader-1 Structure
PROTAC CRBN Degrader-1 structure
CAS No.
2358775-70-7
Chemical Name:
PROTAC CRBN Degrader-1
Synonyms
CRBN PROTAC?14a;PROTAC CRBN Degrader-1;N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosane-1,20-diamide;N'-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethyl)-N-[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]-3,9,12,18-tetraoxaicosanediamide
CBNumber:
CB88054807
Molecular Formula:
C53H72N8O13S
Molecular Weight:
1061.25
MDL Number:
MFCD32197292
MOL File:
Mol file
Last updated:2024-10-23 13:36:13
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PROTAC CRBN Degrader-1 Properties

Boiling point 1241.2±65.0 °C(Predicted)
Density 1.294±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 200 mg/mL (188.46 mM)
form Solid
pka 10.74±0.40(Predicted)
color Light yellow to yellow

PROTAC CRBN Degrader-1 Chemical Properties,Uses,Production

Description

CRBN PROTAC? 14a is a cereblon degrader. It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. It preferentially degrades cereblon, and induces rapid and profound cereblon degradation.

storage

Store at -20°C

PROTAC CRBN Degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC CRBN Degrader-1 Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32112 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1388 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278 sales@ubiochem.com China 4297 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18478 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 13417589054 trendseenbio@gmail.com China 9470 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4870 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 August@easycdmo.com China 10030 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Jilin Province Woda Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Easy CDMO Co.,Ltd 58

View Lastest Price from PROTAC CRBN Degrader-1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PROTAC CRBN Degrader-1 pictures 2024-10-24 PROTAC CRBN Degrader-1
2358775-70-7
 US $987.00 / mg 10g TargetMol Chemicals Inc.

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PROTAC CRBN Degrader-1 CRBN PROTAC?14a N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosane-1,20-diamide N'-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethyl)-N-[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]-3,9,12,18-tetraoxaicosanediamide 2358775-70-7