Phosphinothricin
- CAS No.
- 51276-47-2
- Chemical Name:
- Phosphinothricin
- Synonyms
- C05042;HOE-866;HOE-35956;Glufosite;Phosphinothricin;2'-Anhydrouridine;13C,2H3]-Glufosinate;IAJOBQBIJHVGMQ-UHFFFAOYSA-N;Phosphinothricin ammonium salt;2-amino-4-(hydroxymethylphosphinyl)butyric acid
- CBNumber:
- CB8918965
- Molecular Formula:
- C5H12NO4P
- Molecular Weight:
- 181.13
- MDL Number:
- MFCD00211362
- MOL File:
- 51276-47-2.mol
- MSDS File:
- SDS
Melting point | 229-231° (dec) |
---|---|
Boiling point | 519.1±45.0 °C(Predicted) |
Density | 1.378±0.06 g/cm3(Predicted) |
solubility | Aqueous Acid (Slightly), Methanol (Very Slightly, Sonicated), Water (Slightly) |
pka | 2.22±0.10(Predicted) |
form | Solid |
color | White to Light Beige |
Stability | Hygroscopic |
LogP | -0.750 (est) |
FDA UNII | C8W4FP6BTY |
EPA Substance Registry System | Butanoic acid, 2-amino-4-(hydroxymethylphosphinyl)- (51276-47-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H360-H302-H312-H373 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P260-P314-P501-P280-P302+P352-P312-P322-P363-P501 |
Phosphinothricin price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | G596958 | Glufosinate | 51276-47-2 | 1mg | $50 | 2021-12-16 | Buy |
Usbiological | 286625 | Phosphinothricin | 51276-47-2 | 50mg | $389 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | AGR0000264 | DL-PHOSPHINOTRICIN 95.00% | 51276-47-2 | 250MG | $470 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | AGR0000264 | DL-PHOSPHINOTRICIN 95.00% | 51276-47-2 | 100MG | $498 | 2021-12-16 | Buy |
AK Scientific | J52992 | Glufosinate | 51276-47-2 | 250mg | $250 | 2021-12-16 | Buy |
Phosphinothricin Chemical Properties,Uses,Production
Definition
ChEBI: 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid is a non-proteinogenic alpha-amino acid that is 2-aminobutanoic acid which is substituted at position 4 by a hydroxy(methyl)phosphoryl group. It is a member of phosphinic acids and a non-proteinogenic alpha-amino acid.
Enzyme inhibitor
This dephospho transition-state analogue (FW = 177.10 g/mol; CAS 51276- 47-2) is naturally occurring glutamate analogue, first isolated from Streptomyces viridochromogenes. Phosphonothricin is a slow, tight-binding inhibitor of glutamine synthetase that binds at the glutamate binding site and stabilizes the flap of a glutamyl residue in a position blocking glutamate entry into the active site, thereby trapping the inhibitor on the enzyme. Phosphinothricin undergoes an ATP-dependent phosphorylation. Note: Phosphinothricin is a component of the antibiotics bialaphos and phosalacine. The monoammonium salt of the racemic compound, also called glufosinate-ammonium, is a post-emergent herbicide.
Metabolic pathway
When 14C-phosphinothricin [homoalanin-4-yl- (methyl)phosphinic acid] is incubated in the cell suspension cultures of soybean, wheat, and maize, in maize cells which take up to 50% of the applied radioactivity, four different metabolites are detected which are identified as 4-methylphosphinico-2-oxo- butyric acid, 4-methylphosphinico-2-hydroxybutyric acid, 4-methylphosphinicobutyric acid, and 3- methylphosphinicopropionic acid. In soybean and wheat cultures, 10 and 6% of the applied radioactivity is taken up, respectively. In soybean, only one metabolite, 3-methylphosphinicopropionic acid, is detected, whereas in wheat, 4-methyl- phosphinicobutyric acid is additionally present.
Phosphinothricin Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50003 | 58 |
AS WATER CO., LTD. | +86-18994963526 +8618994963526 | 1346073549@qq.com | United Kingdom | 176 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
View Lastest Price from Phosphinothricin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-08-09 | Phosphinothricin
51276-47-2
|
US $10.00 / kg | 1kg | 99.99% | 50000tons | Henan Bao Enluo International TradeCo.,LTD | ||
2020-11-16 | Glufosinate
51276-47-2
|
US $0.00 / Kg/Bag | 10Kg/Bag | 99% | 20 Tons | Longyan Tianhua Biological Technology Co., Ltd |
- Phosphinothricin
51276-47-2
- US $10.00 / kg
- 99.99%
- Henan Bao Enluo International TradeCo.,LTD
- Glufosinate
51276-47-2
- US $0.00 / Kg/Bag
- 99%
- Longyan Tianhua Biological Technology Co., Ltd