(9R)-6'-methoxycinchonan-9-ol
- CAS No.
- 572-59-8
- Chemical Name:
- (9R)-6'-methoxycinchonan-9-ol
- Synonyms
- (9R)-;Epiquindine;Epiquinidine;9-Epiquinidine;(9R)-6'-methoxycinchonan-9-ol;(8R,9R)-6'-Methoxycinchonan-9-ol;Cinchonan-9-ol, 6'-methoxy-, (9R)-;(R)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol;(R)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
- CBNumber:
- CB8939382
- Molecular Formula:
- C20H24N2O2
- Molecular Weight:
- 324.42
- MDL Number:
- MFCD19686977
- MOL File:
- 572-59-8.mol
- MSDS File:
- SDS
| Melting point | 111-113° |
|---|---|
| alpha | D25 +107.8° (c = 1.02 in ethanol) |
| Boiling point | 462.75°C (rough estimate) |
| Density | 1.1294 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | 2-8°C |
| form | Solid-Liquid Mixture |
| pka | 12.80±0.20(Predicted) |
| color | White to off-white |
| FDA UNII | RN974X9U97 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H317-H334 |
| Precautionary statements | P261-P280-P342+P311 |
| Hazard Codes | Xn |
| Risk Statements | 22-42/43 |
| Safety Statements | 22-36/37-45 |
(9R)-6'-methoxycinchonan-9-ol price More Price(2)
(9R)-6'-methoxycinchonan-9-ol Chemical Properties,Uses,Production
Description
This alkaloid is stereoisomeric with epiQuinine and occurs in 'Quinoidine', the mixture of amorphous bases left after extraction of the four primary alkaloids of Cinchona bark. It crystallizes in colourless leaflets from Et20 and is fluorescent in dilute H2S04, It is dextrorotatory with [α]19D + 102.4° (c 0.8648, EtOH) and furnishes a dihydrochloride, m.p. 195-6°C (dec.); [α]20D + 45.5° (c 0.8012, EtOH); a hydrobromide, m.p. 240°C; thiocyanate, m.p. 193°C; [α]20D + 44.5° (H20) and the dibenzoyl-(+)-tartrate, m.p. 167°C; [α]201D + 3.7° (c 0.8068, EtOH-CHCI 3 ). Catalytic hydrogenation with Pd gives the dihydro derivative, m.p. 122°C; [α]22D + 73.1° (c 0.766, EtOH).
Uses
The 9-epimer of Quinidine (Q685000). Antimalarial.
References
Thron, Dirscherl., Annalen, 521,48 (1935)
(9R)-6'-methoxycinchonan-9-ol Preparation Products And Raw materials
Raw materials
Preparation Products
(9R)-6'-methoxycinchonan-9-ol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Creative Peptides | info@creative-peptides.com | United States | 6084 | 56 | |
| Shanghai Elestone Pharmaceutical Technology Co., Ltd. | 021-36680027/1762825045 | sales2@elestone.com.cn | China | 296 | 58 |
| Shanghai Anyinuo Biomedical Technology Co., Ltd. | 021-34625901 | 420970979@qq.com | China | 5774 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56057 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |