ISOBAVACHALCONE
- CAS No.
- 20784-50-3
- Chemical Name:
- ISOBAVACHALCONE
- Synonyms
- CS-446;ISOBAVACHALCONE;Isobacachalcone;Isobawachalcone;Isobavachalcone-RM;Isobavachalcone/Corylifolinin;Corylifolinin(Isobavachalcone);Isobavachalcone, Akt inhibitor;Isobavachalcone, 10 mM in DMSO;(E)-4,2',4'-Trihydroxy-3'-prenylchalcone
- CBNumber:
- CB91412753
- Molecular Formula:
- C20H20O4
- Molecular Weight:
- 324.37
- MDL Number:
- MFCD00902090
- MOL File:
- 20784-50-3.mol
- MSDS File:
- SDS
| Melting point | 156.8-157.8 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
|---|---|
| Boiling point | 549.0±50.0 °C(Predicted) |
| Density | 1.243±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in DMSO |
| pka | 7.99±0.40(Predicted) |
| form | Yellow oil. |
| color | Yellow-orange |
| FDA UNII | ZWO2SC993A |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P501-P270-P264-P301+P310+P330-P405 |
ISOBAVACHALCONE price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1450 | Isobavachalcone ≥98% (HPCE) | 20784-50-3 | 5mg | $115 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1450 | Isobavachalcone ≥98% (HPCE) | 20784-50-3 | 25mg | $449 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL83317 | Isobavachalcone phyproof? Reference Substance | 20784-50-3 | 10mg | $480 | 2024-03-01 | Buy |
| Cayman Chemical | 19873 | Isobavachalcone ≥98% | 20784-50-3 | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 19873 | Isobavachalcone ≥98% | 20784-50-3 | 10mg | $143 | 2024-03-01 | Buy |
ISOBAVACHALCONE Chemical Properties,Uses,Production
Uses
Isobavachalcone is an inhibitor of platelet aggregation.
Definition
ChEBI: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4' and a prenyl group at position 3'.
Biological Activity
Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia th at inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. It appears th at isobavachalcone modulates both MyD88-dependent and TRIF-dependent signaling of toll-like receptor 4 (TLR4). Isobavachalcone significantly inhibits both oligomerization and fibrillization of Aβ42. Isobavachalcone exhibits a wide spectrum of biological activities including antioxidative, antiplatelet, antimicrobial, anti-inflammatory, antitumor, and neuroprotective.
in vivo
Isobavachalcone (20 mg/kg; intraperitoneal injection; for 0.5-24 hours; female Kunming mice) treatment results in an increase in blood glucose levels, reaching a maximum within 1 hour and maintaining until 4 hours post-dosing[1].
| Animal Model: | Seven-week-old specific pathogen-free female Kunming mice (18-22 g)[1] |
| Dosage: | 20 mg/kg |
| Administration: | Intraperitoneal injection; for 0.5, 1, 2, 4, 6, 8, 12, 24 hours |
| Result: | Increased in blood glucose levels. |
ISOBAVACHALCONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12205 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10244 | 58 |
View Lastest Price from ISOBAVACHALCONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Isobavachalcone
20784-50-3
|
US $55.00-197.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Isobavachalcone
20784-50-3
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2019-07-14 | ISOBAVACHALCONE
20784-50-3
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
-
- Isobavachalcone
20784-50-3
- US $55.00-197.00 / mg
- 99.76%
- TargetMol Chemicals Inc.
-
- Isobavachalcone
20784-50-3
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- ISOBAVACHALCONE
20784-50-3
- US $1.00 / KG
- 99%
- Career Henan Chemical Co