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2’-O-Methyl-rA(N-Bz)phosphoramidite

2’-O-Methyl-rA(N-Bz)phosphoramidite structure

CAS No.: 110782-31-5

Chemical Name:: 2’-O-Methyl-rA(N-Bz)phosphoramidite

Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite;Ac-dA Phosphoramidite;2’-OMe -dA(Bz) Amidite;-2-((bis(4-methoxyphenyl);2'OMe-A CE PhosphoraMidite;N6-Bz-5'-O-DMT-2'-OMe-A-CE;2'-OMe-Bz-A Phosphoramidite;Bz-2'-OMe-rA Phosphoramidite;2'-OMe-A(Bz) Phosphoramidite;2'-OMe-A(Bz) Phosphoramidite

CBNumber:: CB91871624

Molecular Formula:: C48H54N7O8P

Molecular Weight:: 887.96

MDL Number:: MFCD00792622

MOL File:: 110782-31-5.mol

MSDS File:: SDS

Last updated:2024-10-28 23:16:16

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2’-O-Methyl-rA(N-Bz)phosphoramidite Properties

Melting point	93-95°C
storage temp.	Sealed in dry,2-8°C
solubility	Acetonitrile (Sparingly), DMSO (Slightly), Methanol (Slightly)
form	powder
pka	7.87±0.43(Predicted)
color	white to off-white
InChIKey	AZCGOTUYEPXHMJ-DCATYJMPNA-N

SAFETY

Risk and Safety Statements

WGK Germany	3
HS Code	29349990

2’-O-Methyl-rA(N-Bz)phosphoramidite price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A211180	DMT-2′O-Methyl-rA(bz) Phosphoramidite configured for PerkinElmer, configured for Polygen	110782-31-5	1G	$98.7	2024-03-01	Buy
Sigma-Aldrich	A211150	DMT-2′O-Methyl-rA(bz) Phosphoramidite configured for (?KTA? and OligoPilot?), configured for ABI	110782-31-5	2g	$181	2024-03-01	Buy
Sigma-Aldrich	A211100	DMT-2′O-Methyl-rA(bz) Phosphoramidite ≥99% (31P-NMR)	110782-31-5	100g	$6540	2024-03-01	Buy
Sigma-Aldrich	A211100	DMT-2′O-Methyl-rA(bz) Phosphoramidite ≥99% (31P-NMR)	110782-31-5	500g	$32550	2024-03-01	Buy
Sigma-Aldrich	A211180	DMT-2′O-Methyl-rA(bz) Phosphoramidite configured for PerkinElmer, configured for Polygen	110782-31-5	0.5g	$92.7	2024-03-01	Buy

Product number	Packaging	Price	Buy
A211180	1G	$98.7	Buy
A211150	2g	$181	Buy
A211100	100g	$6540	Buy
A211100	500g	$32550	Buy
A211180	0.5g	$92.7	Buy

2’-O-Methyl-rA(N-Bz)phosphoramidite Chemical Properties,Uses,Production

Chemical Properties

White or off-white power

Uses

(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex RNA.

General Description

Proligo′s 2′O-Methyl RNA monomers are compatible with fast deprotectionschemes that are based on the application of aliphatic amines, such asmethylamine. The adenosine and guanosine monomers are protected bythe standard benzoyl (bz) and isobutyryl (ib) groups.2′O-Methyl RNA is a nucleic acid analog that is characterized by theexceptional hybridization properties that it imparts with complimentary DNA or RNA, as well as increased stability against enzymatic degradationcompared to natural nucleic acids.The unique combination of properties of 2′O-Methyl RNA had foundwidespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules

2’-O-Methyl-rA(N-Bz)phosphoramidite synthesis

Synthesis of 2’-O-Methyl-rA(N-Bz)phosphoramidite from 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite and N6-BENZOYL-5'-(DIMETHOXYTRITYL)-2'-O-METHYLADENOSINE

2’-O-Methyl-rA(N-Bz)phosphoramidite Preparation Products And Raw materials

Raw materials

N6-BENZOYL-5'-(DIMETHOXYTRITYL)-2'-O-METHYLADENOSINE 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

Preparation Products

2’-O-Methyl-rA(N-Bz)phosphoramidite Suppliers

Global( 172)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Hengkang Pharmaceutical Co., Ltd.	+86-576-83372028 +86-18868723926	bd1@hengkangpharm.cn	China	119	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18751	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10311	58
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Jinan Liheng Biotechnology Co., Ltd.	15865262812	info@lihengpharm.com	CHINA	938	58

Supplier	Advantage
Zhejiang Hengkang Pharmaceutical Co., Ltd.	58
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Yunbio Tech Co.,Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Jinan Liheng Biotechnology Co., Ltd.	58

View Lastest Price from 2’-O-Methyl-rA(N-Bz)phosphoramidite manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-10-28	2'-OMe-A(Bz) Phosphoramidite 110782-31-5	US $42.00 / mg			10g	TargetMol Chemicals Inc.
2024-08-08	N6-Bz-5'-O-DMT-2'-OMe-A-CE 110782-31-5	US $0.00 / mg	100mg	≥98%	20tons	Hefei Huana Biomedical Technology Co.,Ltd.
2023-04-04	DMT-2'-O-Me-rA(bz) amidite 110782-31-5	US $0.00-0.00 / kg	1kg	98%	200kg per month	Zhejiang Hengkang Pharmaceutical Co., Ltd.

2'-OMe-A(Bz) Phosphoramidite
110782-31-5
US $42.00 / mg
TargetMol Chemicals Inc.

N6-Bz-5'-O-DMT-2'-OMe-A-CE
110782-31-5
US $0.00 / mg
≥98%
Hefei Huana Biomedical Technology Co.,Ltd.

DMT-2'-O-Me-rA(bz) amidite
110782-31-5
US $0.00-0.00 / kg
98%
Zhejiang Hengkang Pharmaceutical Co., Ltd.

110782-31-5(2’-O-Methyl-rA(N-Bz)phosphoramidite)Related Search:

DMT-dG(dmf) Phosphoramidite DMT-2′O-Methyl-rC(ac) Phosphoramidite 2'-O-Methylcytidine DMT-2μ-O-Me-rG(ib) amidite DMT-2′Fluoro-dU Phosphoramidite

2'-O-MOE-A(Bz)-3'-phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite

2'-O-(2-Methoxyethyl)cytidine 2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE

2'-OMe-ibu-G Phosphoramidite 2'-O-(2-Methoxyethyl)guanosine 2'-O-Methyladenosine

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2’-O-Methyl-rA(N-Bz)phosphoramidite N-blocked-5'-O-DMT-2'-O-Me CED adenosine phosphoramidite 5'-O-DMT-2'-O-Me-rA(N-Bz)-3'-CEDPA N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 2'-OMe-Bz-A Phosphoramidite Ac-dA Phosphoramidite 5'-O-DMT-2'-O-Me-A(bz) phosphoramidite 2'OMe-A CE PhosphoraMidite 5'-DiMethoxytrityl-N-benzoyl-Adenosine,2'-O-Methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoraMidite N6-Benzoyl-5'-O-DMT-2'-O-methyl-D-adenosine 3'-CE phosphoramidite DMT-2′O-Methyl-rA(bz) Phosphoramidite 2'-O-Methyl-N6-Benzoyl-5'-O-DMT-Adenosine-3'-CE-Phosphoramidite 5'-DMT-2'-OMe-rA(N-Bz) Phosphoramidite -2-((bis(4-methoxyphenyl) -4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) -5-(6-Benzamido-9H-purin-9-yl) N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl adenosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite N-[9-(5-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-4-{[(2-CYANOETHOXY)(DIISOPROPYLAMINO)PHOSPHANY 2'-OMe-Bz-rA -CE Phosphoramidite Bz-2'-OMe-rA Phosphoramidite N6-benzoyl-5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Adenosine-3'-CE-Phosphoramidite 2'-O-methyladenosine-ce phosphoramidite for abi Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] 2'-OMe-A(Bz) Phosphoramidite 5'-O-DMT-2'-OMe-Bz-A-CE-Phosphoramidite DMT-2'-OME-dA(Bz)-CE-Phosphoramidite DMT-2-OMe-A (Bz) Phosphoramidite 5'-DMTr-2'-O-Me-N6Bz-3'-O-CEP-ADENOSINE (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide 5'-O-DMT-N6-Benzoyl-2'-O-methyladenosine 3'-CE phosphoramidite 5'-O-DMT-2'-OMe-Benzoyl-Adenosine-CE Phosphoramidite DMT-2-O-ME-A-CE Phosphoramidite N6-Bz-5'-O-DMT-2'-OMe-A-CE DMT-2’-OMe-A(Bz)-CE Phosphoramidite 5'-O-DMT-2'-OMe-N6-Benzoyl -Adenosine-3’-Cyanoethyl Phosphoramidite 2'-OMe-N-Bz Adenosine Amidite DMTr-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite 2’-OMe -dA(Bz) Amidite 5'-ODMT-2'-OMe-N-Bz Adenosine-3'-OCEPA 2’-O-Methyl-rA(N-Bz)phosphoramidite 2'-OMe-Bz-A Phosphoramidite DMT-2'-O-Me-A(Bz)-CE Phosphoramidite DMT-2'-O-methyl-rA(Bz) Phosphoramidite 5'-O-DMT-2'-OMe-Benzoyl-Adenosine-CE Phosphoramidite 2'-OMe-A(Bz) Phosphoramidite 2'-OMe-A(Bz)-CE-Phosphoramidite 2'-OMe-Bz-A CE Phosphoramidite N6-Bz-2'-O-Me-5'-O-DMT-A-3'-CE-Phosphoramidite 2'-OMe-rA(Bz)Phosphoramidite N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite N-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-O-methyladenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-DMT-2'-OMe-N6-Benzoyl -Adenosine-3’-Cyanoethyl Phosphoramidite 2'-OMe-N-Bz Adenosine Amidite 110782-31-5 Amidite