ChemicalBook >> CAS DataBase List >>(S)-1-Boc-2-(Hydroxymethyl)piperazine
(S)-1-Boc-2-(Hydroxymethyl)piperazine
- CAS No.
- 1030377-21-9
- Chemical Name:
- (S)-1-Boc-2-(Hydroxymethyl)piperazine
- Synonyms
- (S)-1-Boc-2-(hyroxyMethyl)piperazine;(S)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE;(S)-N1-BOC-2-Hydroxymethyl-piperazine;(2S)-2-(Hydroxymethyl)piperazine, N1-BOC protected;(S)-tert-butyl 2-(hydroxyMethyl)piperazin-1-carboxylate;(S)-tert-butyl 2-(hydroxyMethyl)piperazine-1-carboxylate;tert-butyl (S)-2-(hydroxymethyl)piperazine-1-carboxylate;tert-butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate;1,1-Dimethylethyl (2S)-2-(hydroxymethyl)-1-piperazinecarboxylate;(S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- CBNumber:
- CB9233339
- Molecular Formula:
- C10H20N2O3
- Molecular Weight:
- 216.28
- MDL Number:
- MFCD07772093
- MOL File:
- Mol file
Last updated:2023-10-19 09:29:34
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933599590 |
(S)-1-Boc-2-(Hydroxymethyl)piperazine price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B600445 | (S)-1-Boc-2-hydroxymethyl-piperazine | 1030377-21-9 | 100mg | $85 | 2021-12-16 | Buy |
| Activate Scientific | AS3135 | (S)-1-Boc-2-(Hydroxymethyl)piperazine 95+% ee | 1030377-21-9 | 250mg | $86 | 2021-12-16 | Buy |
| ChemScene | CS-D0657 | (S)-1-Boc-2-Hydroxymethyl-piperazine >97.0% | 1030377-21-9 | 1g | $94 | 2021-12-16 | Buy |
| AK Scientific | X8638 | (S)-1-Boc-(2-Hydroxymethyl)piperazine | 1030377-21-9 | 100mg | $95 | 2021-12-16 | Buy |
| Matrix Scientific | 070014 | (S)-1-Boc-2-(Hydroxymethyl)piperazine 96+% | 1030377-21-9 | 1g | $165 | 2021-12-16 | Buy |
(S)-1-Boc-2-(Hydroxymethyl)piperazine Chemical Properties,Uses,Production
Uses
(S)-1-N-Boc-2-hydroxymethyl piperazine is a heterocyclic compound and can be used as an intermediate in pharmaceutical synthesis.
Uses
(S)-1-Boc-2-hydroxymethyl-piperazine is a heterocyclic building block used in synthetic chemistry.
Reactions
(S)-1-Boc-2-(Hydroxymethyl)piperazine reacts with 1,2-difluoro-4-nitrobenzene to synthesize tert-butyl (S)-4-(2-fluoro-4-nitrophenyl)-2-(hydroxymethyl)piperazine-1-carboxylate. This compound serves as a crucial intermediate in the preparation of the Wee-1 kinase activity inhibitor.
Synthesis
To a solution of (S)-4-benzyl 1-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylate (1.5 g, 4.28 mmol) in MeOH (20 mL), 10 % Pd/C (150 mg) was added. The mixture was stirred at room temperature for 3 hours under H2. Afterwards, the solid was removed by filtration and the filtrate was concentrated to yield (S)-1-Boc-2-(Hydroxymethyl)piperazine (850 mg, 3.93 mmol, 91.82 percent) as a white solid.
Synthesis of (S)-1-Boc-2-(Hydroxymethyl)piperazine from 1,4-Piperazinedicarboxylic acid, 2-(hydroxymethyl)-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester, (2S)-
(S)-1-Boc-2-(Hydroxymethyl)piperazine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 108)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9338 | 55 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7154 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
View Lastest Price from (S)-1-Boc-2-(Hydroxymethyl)piperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | (S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
1030377-21-9
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- (S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
1030377-21-9
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co
1030377-21-9((S)-1-Boc-2-(Hydroxymethyl)piperazine)Related Search:
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(R)-1-N-Boc-2-(hydroxymethyl)piperazine
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(S)-1-N-BOC-2-METHOXYMETHYLPIPERAZINE
1of4
(2S)-2-(Hydroxymethyl)piperazine, N1-BOC protected
tert-Butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate, (2S)-1-(tert-Butoxycarbonyl)-2-(hydroxymethyl)piperazine
tert-butyl (S)-2-(hydroxymethyl)piperazine-1-carboxylate
tert-butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate
(S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
(S)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE
1-PIPERAZINECARBOXYLIC ACID, 2-(HYDROXYMETHYL)-, 1,1-DIMETHYLETHYL ESTER, (2S)-
(S)-tert-butyl 2-(hydroxyMethyl)piperazin-1-carboxylate
(S)-tert-butyl 2-(hydroxyMethyl)piperazine-1-carboxylate
(S)-1-Boc-2-(hyroxyMethyl)piperazine
1,1-Dimethylethyl (2S)-2-(hydroxymethyl)-1-piperazinecarboxylate
(2S)-2-(hydroxymethyl)-1-Piperazinecarboxylic acid tert-butyl ester
(S)-N1-BOC-2-Hydroxymethyl-piperazine
1030377-21-9