(S)-1-BOC-2-ヒドロキシメチルピペラジン
(S)-1-BOC-2-ヒドロキシメチルピペラジン 物理性質
- 沸点 :
- 324℃
- 比重(密度) :
- 1.085
- 闪点 :
- 150℃
- 貯蔵温度 :
- under inert gas (nitrogen or Argon) at 2–8 °C
- 酸解離定数(Pka):
- 14.97±0.10(Predicted)
(S)-1-BOC-2-ヒドロキシメチルピペラジン 価格
もっと(12)
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01COBOR-7175 |
(S)-1-Boc-2-hydroxymethyl-piperazine |
1030377-21-9 |
1g |
¥40000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01MAS070014 |
(S)-1-Boc-2-(Hydroxymethyl)piperazine |
1030377-21-9 |
10g |
¥364300 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01APOOR308073 |
(2S)-2-(Hydroxymethyl)piperazine, N1-BOC protected |
1030377-21-9 |
1g |
¥43700 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01MAS070014 |
(S)-1-Boc-2-(Hydroxymethyl)piperazine |
1030377-21-9 |
1g |
¥75900 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01MAS070014 |
(S)-1-Boc-2-(Hydroxymethyl)piperazine |
1030377-21-9 |
5g |
¥236900 |
2024-03-01 |
購入 |
(S)-1-BOC-2-ヒドロキシメチルピペラジン 化学特性,用途語,生産方法
反応性
(S)-1-Boc-2-(Hydroxymethyl)piperazine reacts with 1,2-difluoro-4-nitrobenzene to synthesize tert-butyl (S)-4-(2-fluoro-4-nitrophenyl)-2-(hydroxymethyl)piperazine-1-carboxylate. This compound serves as a crucial intermediate in the preparation of the Wee-1 kinase activity inhibitor.
合成
To a solution of (S)-4-benzyl 1-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylate (1.5 g, 4.28 mmol) in MeOH (20 mL), 10 % Pd/C (150 mg) was added. The mixture was stirred at room temperature for 3 hours under H2. Afterwards, the solid was removed by filtration and the filtrate was concentrated to yield (S)-1-Boc-2-(Hydroxymethyl)piperazine (850 mg, 3.93 mmol, 91.82 percent) as a white solid.
(S)-1-BOC-2-ヒドロキシメチルピペラジン 上流と下流の製品情報
原材料
準備製品
(S)-1-BOC-2-ヒドロキシメチルピペラジン 生産企業
Global( 109)Suppliers
(S)-1-BOC-2-ヒドロキシメチルピペラジン スペクトルデータ(1HNMR)
1030377-21-9((S)-1-BOC-2-ヒドロキシメチルピペラジン)キーワード:
- 1030377-21-9
- (2S)-2-(Hydroxymethyl)piperazine, N1-BOC protected
- tert-Butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate, (2S)-1-(tert-Butoxycarbonyl)-2-(hydroxymethyl)piperazine
- tert-butyl (S)-2-(hydroxymethyl)piperazine-1-carboxylate
- tert-butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate
- (S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- (S)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE
- 1-PIPERAZINECARBOXYLIC ACID, 2-(HYDROXYMETHYL)-, 1,1-DIMETHYLETHYL ESTER, (2S)-
- (S)-tert-butyl 2-(hydroxyMethyl)piperazin-1-carboxylate
- (S)-tert-butyl 2-(hydroxyMethyl)piperazine-1-carboxylate
- (S)-1-Boc-2-(hyroxyMethyl)piperazine
- 1,1-Dimethylethyl (2S)-2-(hydroxymethyl)-1-piperazinecarboxylate
- (2S)-2-(hydroxymethyl)-1-Piperazinecarboxylic acid tert-butyl ester
- (S)-N1-BOC-2-Hydroxymethyl-piperazine
- (S)-1-BOC-2-ヒドロキシメチルピペラジン