ChemicalBook >> CAS DataBase List >>1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
- CAS No.
- 446292-08-6
- Chemical Name:
- 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
- Synonyms
- (S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione;Rivaroxaban-5;C22HjgNzO6;Rivaroxaban G;Rivaroxaban ImpVI;2-Amino-13-picoline;RIVAROXABAN EP IMP G;Rivaroxaban Intermediate5;Rivaroxaban EP Impurity G;Rivaroxaban Impurities365
- CBNumber:
- CB92468058
- Molecular Formula:
- C22H19N3O6
- Molecular Weight:
- 421.4
- MDL Number:
- MFCD11977665
- MOL File:
- 446292-08-6.mol
- MSDS File:
- SDS
Last updated:2023-05-25 17:24:36
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Properties
Melting point | 213-215°C |
---|---|
Boiling point | 702.9±55.0 °C(Predicted) |
Density | 1.465±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
pka | 0.99±0.20(Predicted) |
form | Solid |
color | White to Off-White |
Water Solubility | 12mg/L at 20℃ |
LogP | -0.2 at 25℃ |
FDA UNII | 2XRK8YBC47 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | P385850 | 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone | 446292-08-6 | 25mg | $120 | 2021-12-16 | Buy |
TRC | P385850 | 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone | 446292-08-6 | 50mg | $155 | 2021-12-16 | Buy |
TRC | P385850 | 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone | 446292-08-6 | 100mg | $185 | 2021-12-16 | Buy |
AK Scientific | Z6156 | 1H-Isoindole-1,3(2H)-dione,2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- | 446292-08-6 | 25g | $901 | 2021-12-16 | Buy |
Matrix Scientific | 092112 | (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)isoindoline-1,3-dione 95+% | 446292-08-6 | 1g | $975 | 2021-12-16 | Buy |
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Chemical Properties,Uses,Production
Uses
1H-isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- is an important intermediate for the synthesis of rivaroxaban, which is an anticoagulant and the first orally active direct factor Xa inhibitor.
Chemical Properties
White Solid
Uses
Rivaroxaban intermediate.
Flammability and Explosibility
Non flammable
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 310)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 906 | 58 |
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View Lastest Price from 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2023-05-26 | 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4- morpholinyl)phenyl]-5- oxazolidinyl]methyl]-1H-isoindole- 1,3(2H)-dione
446292-08-6
|
US $0.00-0.00 / Kg | 1Kg | 99% | 1-10000kgs | Changzhou Rokechem Technology Co., Ltd. | |
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2022-10-07 | 1H-ISOindole-1,3(2H) -Dione, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHolinyl)PHENYL] -5-OXAZolidinyl]METHYL]-
446292-08-6
|
US $30.00-28.00 / Kg | 1Kg | 99.0% up | 50 tons per month | Xinxiang Hongqi District Houyuan Trading Co.,Ltd | |
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2022-09-20 | (R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
446292-08-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4- morpholinyl)phenyl]-5- oxazolidinyl]methyl]-1H-isoindole- 1,3(2H)-dione
446292-08-6
- US $0.00-0.00 / Kg
- 99%
- Changzhou Rokechem Technology Co., Ltd.
-
- 1H-ISOindole-1,3(2H) -Dione, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHolinyl)PHENYL] -5-OXAZolidinyl]METHYL]-
446292-08-6
- US $30.00-28.00 / Kg
- 99.0% up
- Xinxiang Hongqi District Houyuan Trading Co.,Ltd
-
- (R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
446292-08-6
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
446292-08-6(1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-)Related Search:
Rivaroxaban Metabolite 8
AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
2-ThiophenecarboxaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]-
5-R-Rivaroxaban
Rivaroxaban
POLYSTYRENE IODOSOACETATE
1,2-Cyclohexanedione
(S)-(+)-Epichlorohydrin
4-(4-NITROPHENYL)MORPHOLIN-3-ONE
(S)-(+)-Glycidyl Phthalimide
1of4
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
2-({(5S)-2-oxo-3-[4-(3-oxoMorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}Methyl)-1H-isoindole-1,3(2H)-dione
RivaroxabanInterMediates-01
4-[4-[(5S)-5-PhthaliMidoMethyl-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone
2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione
Rivaroxaban Intermediate5
Rivaroxaban Phthalimido Impurity
2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}
2 - [[(5S) -2- oxo-3- [4- (3-oxo - (morpholin-4-yl)) phenyl] -5-oxazolidinyl] methyl] lH- isoindole -1,3 (2H) - dione
2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
(R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
Rivaroxaban ImpVI
Rivaroxaban impurity 4/2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione
2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dion
Rivaroxaban G
(S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
(Rivaroxaban)
Rivaroxaban EP Impurity G
2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-1H-ISOINDOLE-1,3(2H)-DIONE CAS: 446292-08-6
Rivaroxaban PTH Imp/Rivaroxaban EP Impurity G
2-Amino-13-picoline
2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazoli...
Rivaroxaban Impurities365
TIANFUCHEM--446292-08-6---1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
Rivaroxaban EP Impurity GQ: What is
Rivaroxaban EP Impurity G Q: What is the CAS Number of
Rivaroxaban EP Impurity G Q: What is the storage condition of
Rivaroxaban EP Impurity G Q: What are the applications of
Rivaroxaban EP Impurity G
(S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione
Rivaroxaban-5
(S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazoli
4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone (or) 1H-isoindole-1,3 (2H)-Dione, 2-[[(5S)-2-Oxo-3-[4-(3-Oxo-4Morpholinyl)Phenyl]-5-Oxazolidinyl]methyl
2-[[(5S)-2-Oxo-3-[4-(3-oxo -4-morpholinyl)phenyl]-5-o xazolidinyl]methyl]-1H-isoi ndole-1,3(2H)
C22HjgNzO6
2- [(5S) -2-oxo-3- [4- (3-oxo-4-morphinyl) phenyl] -5-oxazolyl] methyl] -1H-isoindole-1,3 (2H) - dione
Intermediate of Rivaroxaban 3
RIVAROXABAN EP IMP G
446292-08-6
Chiral Reagents
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Intermediate of Rivaroxaban