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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine structure

CAS No.: 1421372-94-2

Chemical Name:: N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

Synonyms: N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine;N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine;AZD9291 1;EOS-61221;AZD9291 N-3;Osimertinib N-3;AZD9291 Intermediate 2;OSIMERTINIB INTERMEDIATE 1;Osimertinib mesylate intermediate 1;N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)p...

CBNumber:: CB92710519

Molecular Formula:: C20H16FN5O3

Molecular Weight:: 393.37

MDL Number:: MFCD28167946

MOL File:: 1421372-94-2.mol

MSDS File:: SDS

Last updated:2024-04-09 22:15:29

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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Properties

Melting point	>250°C (dec.)
Boiling point	639.3±65.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
solubility	DMSO (Slightly, Heated)
pka	2.02±0.10(Predicted)
form	Solid
color	Light Yellow to Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H335-H319
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	F597516	N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine	1421372-94-2	1g	$80	2021-12-16	Buy
ChemScene	CS-M2844	2-Pyrimidinamine,N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)- 99.70%	1421372-94-2	5g	$119	2021-12-16	Buy
Matrix Scientific	153196	N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine 95%	1421372-94-2	5g	$145	2021-12-16	Buy
AK Scientific	0010AP	N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine	1421372-94-2	5g	$208	2021-12-16	Buy
Matrix Scientific	153196	N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine 95%	1421372-94-2	25g	$385	2021-12-16	Buy

Product number	Packaging	Price	Buy
F597516	1g	$80	Buy
CS-M2844	5g	$119	Buy
153196	5g	$145	Buy
0010AP	5g	$208	Buy
153196	25g	$385	Buy

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Chemical Properties,Uses,Production

Uses

N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine functions as a reagent in the synthesis of dihydropyrroloquinoline derivatives with anticancer activity as EGFR modulator to inhibit L858R/T790M.

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine synthesis

Synthesis of N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine from 3-(2-chloropyriMidin-4-yl)-1-Methylindole and 4-fluoro-2-Methoxy-5-nitroaniline

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Preparation Products And Raw materials

Raw materials

3-(2-chloropyriMidin-4-yl)-1-Methylindole 4-fluoro-2-Methoxy-5-nitroaniline 1-Methylindole 2,4-DIFLUORO-5-NITROANILINE 3-(2-chloropyriMidin-4-yl)-1H-indole

4-FLUORO-2-METHOXYANILINE Indole 2,4-Difluoroaniline

1of2

Preparation Products

AZ 7550

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Suppliers

Global( 233)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Victorypharm Co.,Ltd.	+86-13916956214	sales@victory-pharm.com	China	1301	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20318	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29798	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	16208	58
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	341	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29897	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	925	58
Hangzhou Cyanochem Co., Ltd.	+86 17788583750	sales@cyanochem.com	CHINA	283	58

Supplier	Advantage
Suzhou Victorypharm Co.,Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Shanghai Yingrui Biopharma Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58
Hangzhou Cyanochem Co., Ltd.	58

View Lastest Price from N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-09	N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 1421372-94-2	US $5.00-0.10 / KG	1KG	98%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-04-26	N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 1421372-94-2	US $100.00 / kg	1kg	99%	100 tons	Hebei Duling International Trade Co. LTD
2022-09-17	N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 1421372-94-2	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
1421372-94-2
US $5.00-0.10 / KG
98%
Henan Fengda Chemical Co., Ltd

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
1421372-94-2
US $100.00 / kg
99%
Hebei Duling International Trade Co. LTD

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
1421372-94-2
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

1421372-94-2(N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine)Related Search:

AZD-9291 N-(5-Chloro-2-methylphenyl)-7- nitrobenzo[c][1,2,5]oxadiazol-4-amine N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE 1,4-BenzenediaMine, N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]-2-nitro- Mutated EGFR-IN-1

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 2-PyriMidinaMine, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methyl-1H-indol-3-yl)- (4-Fluoro-2-methoxy-5-nitro-phenyl)-[4-(1-methyl-1h-indol-3-yl)-pyrimidin-2-yl]-amine AZD9291 1 OSIMERTINIB INTERMEDIATE 1 N-(4-fluoro-2-methoxy-5-nitrophenyl)- 4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) EOS-61221 N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-3-indolyl)-2-pyrimidinamine AZD9291 N-3 Osimertinib mesylate intermediate 1 AZD9291 Intermediate 2 N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)p... N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine,99% Osimertinib N-3 1421372-94-2 AZD9291 1421372-94-2