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ACK1-B19

ACK1-B19 structure

CAS No.: 1234480-46-6

Chemical Name:: ACK1-B19

Synonyms: CS-2588;XMD8-87;ACK1-B19;XMD8-87 (ACK1-B19);XMD-8-87;XMD8 87;XMD 8 87;Tyrosinase,Inhibitor,inhibit,XMD8 87,XMD-8-87,XMD887,XMD8-87;2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;2-[[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-

CBNumber:: CB92716117

Molecular Formula:: C24H27N7O2

Molecular Weight:: 445.52

MDL Number:: MFCD30742941

MOL File:: 1234480-46-6.mol

Last updated:2024-07-02 08:55:41

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ACK1-B19 Properties

Density	1.283±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form	A crystalline solid
pka	10.18±0.20(Predicted)
color	White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

ACK1-B19 price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	23354	XMD8-87 ≥98%	1234480-46-6	1mg	$32	2024-03-01	Buy
Cayman Chemical	23354	XMD8-87 ≥98%	1234480-46-6	5 mg	$95	2024-03-01	Buy
Cayman Chemical	23354	XMD8-87 ≥98%	1234480-46-6	10mg	$191	2023-01-06	Buy
Tocris	6061	XMD8-87 ≥98%(HPLC)	1234480-46-6	10	$183	2021-12-16	Buy
Tocris	6061	XMD8-87 ≥98%(HPLC)	1234480-46-6	50	$771	2021-12-16	Buy

Product number	Packaging	Price	Buy
23354	1mg	$32	Buy
23354	5 mg	$95	Buy
23354	10mg	$191	Buy
6061	10	$183	Buy
6061	50	$771	Buy

ACK1-B19 Chemical Properties,Uses,Production

Description

XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC₅₀ value of 1.9 μM in HEK293T cells expressing human TNK2. It is selective for TNK2 over a panel of approximately 100 kinases with >90 and <50% inhibition for TNK2 and all other kinases tested, respectively. XMD8-87 inhibits growth of Ba/F3 cells expressing constitutively active mutant TNK2s (IC₅₀s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC₅₀ = >1 μM).

Uses

XMD8-87 is used in the studies of benzopyrimidodiazepinones as most selective and potent ERK5 inhibitor.

ACK1-B19 Preparation Products And Raw materials

Raw materials

Preparation Products

ACK1-B19 Suppliers

Global( 58)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29826	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58

View Lastest Price from ACK1-B19 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-23	ACK1-B19 1234480-46-6	US $1.00 / g	1g	99.99%	200kg	Career Henan Chemical Co

ACK1-B19
1234480-46-6
US $1.00 / g
99.99%
Career Henan Chemical Co

ACK1-B19 Spectrum

ACK1-B19(1234480-46-6)¹HNMR

1234480-46-6(ACK1-B19)Related Search:

XMD17-51 XMD17 109 XMD-17-51 Trifluoroacetate 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one XMD16-5

6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-

1of2

ACK1-B19 XMD8-87 CS-2588 XMD-8-87;XMD8 87;XMD 8 87 2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one 5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl- XMD8-87 (ACK1-B19) 2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one Tyrosinase,Inhibitor,inhibit,XMD8 87,XMD-8-87,XMD887,XMD8-87 2-[[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one 1234480-46-6