Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> ACK1-B19

ACK1-B19

ACK1-B19 price.
  • $32 - $1056
  • Product name: ACK1-B19
  • CAS: 1234480-46-6
  • MF: C24H27N7O2
  • MW: 445.52
  • EINECS:
  • MDL Number:MFCD30742941
  • Synonyms:ACK1-B19;XMD8-87;CS-2588;XMD-8-87;XMD8 87;XMD 8 87;2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-;XMD8-87 (ACK1-B19)
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 50
  • 5mg
  • 2x5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 5 mg
  • ManufacturerAK Scientific
  • Product number6234DK
  • Product description2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
  • Packaging1mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA560552
  • Product descriptionXMD8-87 97%
  • Packaging5mg
  • Price$181
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA560552
  • Product descriptionXMD8-87 97%
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA560552
  • Product descriptionXMD8-87 97%
  • Packaging25mg
  • Price$424
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2762
  • Product descriptionXMD8-87 98%
  • Packaging2x5mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2762
  • Product descriptionXMD8-87 98%
  • Packaging25mg
  • Price$357.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23354
  • Product descriptionXMD8-87 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23354
  • Product descriptionXMD8-87 ≥98%
  • Packaging5 mg
  • Price$95
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23354
  • Product descriptionXMD8-87 ≥98%
  • Packaging10mg
  • Price$191
  • Updated2023-01-06
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6438
  • Product descriptionXMD8-87 98.29%
  • Packaging5mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6438
  • Product descriptionXMD8-87 98.29%
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6438
  • Product descriptionXMD8-87 98.29%
  • Packaging25mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6438
  • Product descriptionXMD8-87 98.29%
  • Packaging50mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6438
  • Product descriptionXMD8-87 98.29%
  • Packaging100mg
  • Price$1056
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9940
  • Product descriptionXMD8-87 >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6061
  • Product descriptionXMD8-87 ≥98%(HPLC)
  • Packaging10
  • Price$183
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6234DK 2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one 1mg $187 2021-12-16 Buy
Ambeed A560552 XMD8-87 97% 5mg $181 2021-12-16 Buy
Ambeed A560552 XMD8-87 97% 10mg $250 2021-12-16 Buy
Ambeed A560552 XMD8-87 97% 25mg $424 2021-12-16 Buy
Axon Medchem Axon2762 XMD8-87 98% 2x5mg $154 2021-12-16 Buy
Axon Medchem Axon2762 XMD8-87 98% 25mg $357.5 2021-12-16 Buy
Cayman Chemical 23354 XMD8-87 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 23354 XMD8-87 ≥98% 5 mg $95 2024-03-01 Buy
Cayman Chemical 23354 XMD8-87 ≥98% 10mg $191 2023-01-06 Buy
ChemScene CS-6438 XMD8-87 98.29% 5mg $132 2021-12-16 Buy
ChemScene CS-6438 XMD8-87 98.29% 10mg $192 2021-12-16 Buy
ChemScene CS-6438 XMD8-87 98.29% 25mg $420 2021-12-16 Buy
ChemScene CS-6438 XMD8-87 98.29% 50mg $660 2021-12-16 Buy
ChemScene CS-6438 XMD8-87 98.29% 100mg $1056 2021-12-16 Buy
DC Chemicals DC9940 XMD8-87 >98% 100mg $550 2021-12-16 Buy
Tocris 6061 XMD8-87 ≥98%(HPLC) 10 $183 2021-12-16 Buy
Next Last

Properties

Density :1.283±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :10.18±0.20(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μM in HEK293T cells expressing human TNK2. It is selective for TNK2 over a panel of approximately 100 kinases with >90 and <50% inhibition for TNK2 and all other kinases tested, respectively. XMD8-87 inhibits growth of Ba/F3 cells expressing constitutively active mutant TNK2s (IC50s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC50 = >1 μM).

More related product prices

6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- XMD16-5 1234480-50-2 XMD17 109

Related product price

Suppliers and manufacturers

career henan chemical co
ACK1-B19
$1.00 /1g
ACK1-B19 CAS:1234480-46-6
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific
Amadis Chemical Company Limited