ChemicalBook >> CAS DataBase List >>LY-3177833
LY-3177833
- CAS No.
- 1627696-51-8
- Chemical Name:
- LY-3177833
- Synonyms
- CS-2783;LY-3177833;LY 3177833;LY-3177833;LY3177833,CDK,Cyclin dependent kinase,Inhibitor,inhibit,LY 3177833;(R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)isoindolin-1-one;1H-Isoindol-1-one, 3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-, (3R)-
- CBNumber:
- CB93139438
- Molecular Formula:
- C16H12FN5O
- Molecular Weight:
- 309.3
- MDL Number:
- MFCD30533280
- MOL File:
- 1627696-51-8.mol
Last updated:2024-07-02 08:55:41
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H302-H315-H318-H334-H317-H341-H361-H370-H335-H413 | |||||||||
Precautionary statements | P201-P202-P260-P264-P270-P272-P273-P280-P284-P301+P312-P302+P352-P304+P341-P305+P351+P338-P310-P308+P313-P321-P330-P362+P364-P333+P313-P342+P311-P363-P405-P501 | |||||||||
NFPA 704 |
|
LY-3177833 price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 25988 | LY3177833 ≥98% | 1627696-51-8 | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 25988 | LY3177833 ≥98% | 1627696-51-8 | 10mg | $166 | 2024-03-01 | Buy |
Cayman Chemical | 25988 | LY3177833 ≥98% | 1627696-51-8 | 25mg | $388 | 2024-03-01 | Buy |
Cayman Chemical | 25988 | LY3177833 ≥98% | 1627696-51-8 | 50mg | $728 | 2024-03-01 | Buy |
AK Scientific | 7406DY | CID81689696 | 1627696-51-8 | 50mg | $910 | 2021-12-16 | Buy |
LY-3177833 Chemical Properties,Uses,Production
Description
LY3177833 is an orally bioavailable inhibitor of Cdc7 kinase (IC50 = 3.3 nM for ADP production in an enzyme assay). It inhibits phosphorylation of MCM2-S53 in H1299 cells (IC50 = 0.29 μM). LY3177833 reduces tumor growth in an SW620 human colorectal adenocarcinoma mouse xenograft model when administered at doses of 10, 20, and 30 mg/kg twice per day.
LY-3177833 Preparation Products And Raw materials
Raw materials
Preparation Products
LY-3177833 Suppliers
Global( 47)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29820 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6008 | 61 |
LY-3177833
(R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)isoindolin-1-one
LY 3177833;LY-3177833
CS-2783
1H-Isoindol-1-one, 3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-, (3R)-
LY3177833,CDK,Cyclin dependent kinase,Inhibitor,inhibit,LY 3177833
1627696-51-8