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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

CAS No.
39028-27-8
Chemical Name:
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
Synonyms
SIA;SIA Crosslinker;NHS IODOACETATE;N-IodoacetoxysucciniMide;Succinimidyl iodoacetate;N-SUCCINIMIDYL IODOACETATE;SIA (succinimidyl iodoacetate);N-Succinimidyl Iodoacetate >N-SucciniMidyl iodoacetate(SIA);N-Succinimidyl Iodoacetate, 95+%
CBNumber:
CB9364435
Molecular Formula:
C6H6INO4
Molecular Weight:
283.02
MDL Number:
MFCD00058451
MOL File:
39028-27-8.mol
Last updated:2024-10-23 13:36:13

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Properties

Melting point 148°C
Boiling point 315.6±44.0 °C(Predicted)
Density 2.11±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 50 mg/mL
form powder
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29251900
NFPA 704
0
2 0

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I9760 Iodoacetic acid N-hydroxysuccinimide ester powder 39028-27-8 100mg $264 2024-03-01 Buy
Sigma-Aldrich I9760 Iodoacetic acid N-hydroxysuccinimide ester powder 39028-27-8 50mg $304 2024-03-01 Buy
TCI Chemical S0844 N-Succinimidyl Iodoacetate >95.0%(N) 39028-27-8 100mg $235 2024-03-01 Buy
TRC S690290 N-Succinimidyl Iodoacetate 39028-27-8 50mg $80 2021-12-16 Buy
Chem-Impex 22998 Succinimidyliodoacetate,≥98%(HPLC) ≥98%(HPLC) 39028-27-8 250MG $122.3 2021-12-16 Buy
Product number Packaging Price Buy
I9760 100mg $264 Buy
I9760 50mg $304 Buy
S0844 100mg $235 Buy
S690290 50mg $80 Buy
22998 250MG $122.3 Buy

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Chemical Properties,Uses,Production

Description

SIA Crosslinker is a non-cleavable, water-soluble crosslinker containig an NHS ester and an iodine group. The NHS ester is reactive toward amines while the iodine reacts with thiol groups.

Chemical Properties

White Solid

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms

Uses

forms water soluble carboxylate derivatives

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms

Biological Activity

SIA Crosslinker is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 154)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 17777 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58

View Lastest Price from IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SIA Crosslinker pictures 2024-10-24 SIA Crosslinker
39028-27-8
US $0.00 / mg 10g TargetMol Chemicals Inc.
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER pictures 2021-07-13 IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
39028-27-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER pictures 2021-07-09 IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
39028-27-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
N-HydroxysucciniMide Iodoacetic Acid Ester N-IodoacetoxysucciniMide Iodoacetic Acid N-Succinimidyl Ester N-(Iodoacetoxy)succinimide 2,5-Pyrrolidinedione, 1-[(iodoacetyl)oxy]- N-SucciniMidyl iodoacetate(SIA) SIA N-HYDROXYSUCCINIMIDYL IODOACETATE NHS IODOACETATE N-SUCCINIMIDYL IODOACETATE SIA Crosslinker Iodoacetic acid N-hydroxysuccinimide ester powder 2,5-Dioxopyrrolidin-1-yl 2-iodoacetate IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Succinimidyl iodoacetate SIA (succinimidyl iodoacetate) 2-Iodoacetate N-Succinimidyl Ester N-Succinimidyl Iodoacetate > Acetic acid, 2-iodo-, 2,5-dioxo-1-pyrrolidinyl ester Iodoacetic Acid N-Succinimidyl Ester N-Succinimidyl Iodoacetate, 95+% 39028-27-8 C6H6INO4 C6H6NO4I BioChemical Crosslinking Heterobifunctional Cross-Linking Reagents Proteomics and Protein Expression Protein Modification Proteomics MTS and Sulfhydryl Active Reagents Heterobifunctional Crosslinker heteroXlink Cross Linking Reagents MTS & Sulfhydryl Active Reagents Active Esters/AdditivesProtein Modification Active Esters/AdditivesSynthetic Reagents Coupling Crosslinking Heterobifunctional Cross-Linking Reagents Peptide Synthesis