CASPASE INHIBITOR3
- CAS No.
- 187389-53-3
- Chemical Name:
- CASPASE INHIBITOR3
- Synonyms
- N-BOC-D-FMK;CASPASE INHIBITOR3;Boc-D-FMK/Boc-Asp(OMe)-fluoromethyl ketone;Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAF;N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone;Methyl (S)-3-((tert-butoxycarbonyl)amino)-5-fluoro-4-oxopentanoate;(S)-methyl 3-((tert-butoxycarbonyl)amino)-5-fluoro-4-oxopentanoate;(3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid methyl ester;Pentanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-, methyl ester, (3S)-;inhibit,broad,Boc Asp(OMe) fluoromethyl ketone,Caspase,Fas-induced,Inhibitor,LDH,oxidative,apoptosis,spontaneous,BocAsp(OMe)fluoromethyl ketone,rupture
- CBNumber:
- CB9390865
- Molecular Formula:
- C11H18FNO5
- Molecular Weight:
- 263.26
- MDL Number:
- MFCD07370667
- MOL File:
- 187389-53-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Safety Statements | 22-24/25 |
---|---|
WGK Germany | 3 |
CASPASE INHIBITOR3 price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | B2682 | Boc-Asp(OMe)-fluoromethyl ketone ≥90% (TLC), solid | 187389-53-3 | 3mg | $1020 | 2024-03-01 | Buy |
Alfa Aesar | J65812 | N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone | 187389-53-3 | 5mg | $463.65 | 2024-03-01 | Buy |
Cayman Chemical | 16118 | Boc-D-FMK ≥95% | 187389-53-3 | 500μg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 16118 | Boc-D-FMK ≥95% | 187389-53-3 | 1mg | $96 | 2024-03-01 | Buy |
Cayman Chemical | 16118 | Boc-D-FMK ≥95% | 187389-53-3 | 5mg | $388 | 2024-03-01 | Buy |
CASPASE INHIBITOR3 Chemical Properties,Uses,Production
Uses
N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone is used as a novel Boc-D(OMe)-FMK inhibitor synthesized using proprietary technology and irreversibly binds to activated caspases to block apoptosis. It is useful for in vitro and in vivo applications.
Uses
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus proliferation in chorion cells , as a component of the transplantation medium for the transplantation of human embryonic stem cells (ESC)-derived medial ganglionic eminence (MGE) cells into hippocampus of mice , as a protease inhibitor to study its effects on cell death in parasites .
Biochem/physiol Actions
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10.
CASPASE INHIBITOR3 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7621 | 58 |
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 | sales@tihondan.com | China | 3741 | 58 |
Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 6000 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Hangzhou Baige Pharmaceutical Technology Co. , Ltd. | 0571-85350119 15888826472 | 15888826472@163.com | China | 2729 | 58 |
Hangzhou Beiputai Biopharmaceutical Co., Ltd | 0571-85350119 13305819357 | bptsales@163.com | China | 3850 | 58 |
VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
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