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CASPASE INHIBITOR3

CASPASE INHIBITOR3 Structure
CASPASE INHIBITOR3 structure
CAS No.
187389-53-3
Chemical Name:
CASPASE INHIBITOR3
Synonyms
N-BOC-D-FMK;CASPASE INHIBITOR3;Boc-D-FMK/Boc-Asp(OMe)-fluoromethyl ketone;Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAF;N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone;Methyl (S)-3-((tert-butoxycarbonyl)amino)-5-fluoro-4-oxopentanoate;(S)-methyl 3-((tert-butoxycarbonyl)amino)-5-fluoro-4-oxopentanoate;(3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid methyl ester;Pentanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-, methyl ester, (3S)-;inhibit,broad,Boc Asp(OMe) fluoromethyl ketone,Caspase,Fas-induced,Inhibitor,LDH,oxidative,apoptosis,spontaneous,BocAsp(OMe)fluoromethyl ketone,rupture
CBNumber:
CB9390865
Molecular Formula:
C11H18FNO5
Molecular Weight:
263.26
MDL Number:
MFCD07370667
MOL File:
187389-53-3.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33
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CASPASE INHIBITOR3 Properties

Boiling point 383.5±37.0 °C(Predicted)
Density 1.150±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. -20°C
solubility Soluble in dry DMSO or DMF at approximately 20mM. Store stock solutions at -20°C.
pka 10.12±0.46(Predicted)
form Powder
color Off-white

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

CASPASE INHIBITOR3 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B2682 Boc-Asp(OMe)-fluoromethyl ketone ≥90% (TLC), solid 187389-53-3 3mg $1020 2024-03-01 Buy
Alfa Aesar J65812 N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone 187389-53-3 5mg $463.65 2024-03-01 Buy
Cayman Chemical 16118 Boc-D-FMK ≥95% 187389-53-3 500μg $62 2024-03-01 Buy
Cayman Chemical 16118 Boc-D-FMK ≥95% 187389-53-3 1mg $96 2024-03-01 Buy
Cayman Chemical 16118 Boc-D-FMK ≥95% 187389-53-3 5mg $388 2024-03-01 Buy
Product number Packaging Price Buy
B2682 3mg $1020 Buy
J65812 5mg $463.65 Buy
16118 500μg $62 Buy
16118 1mg $96 Buy
16118 5mg $388 Buy

CASPASE INHIBITOR3 Chemical Properties,Uses,Production

Uses

N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone is used as a novel Boc-D(OMe)-FMK inhibitor synthesized using proprietary technology and irreversibly binds to activated caspases to block apoptosis. It is useful for in vitro and in vivo applications.

Uses

Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus proliferation in chorion cells , as a component of the transplantation medium for the transplantation of human embryonic stem cells (ESC)-derived medial ganglionic eminence (MGE) cells into hippocampus of mice , as a protease inhibitor to study its effects on cell death in parasites .

Biochem/physiol Actions

Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10.

CASPASE INHIBITOR3 Preparation Products And Raw materials

Raw materials

Preparation Products

CASPASE INHIBITOR3 Suppliers

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		+8618235132063 sales@tihondan.com China 3741 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740 sales@bicbiotech.com China 5994 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859 Intermediate@cato-chem.com China 8056 58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd. 0571-85350119 15888826472 15888826472@163.com China 2729 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Jinan Carbotang Biotech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd 		58
Nanjing Bicbiotechnology Co., Ltd 		58
Aladdin Scientific 		58
Guangzhou CATO Research Chemicals Inc. 		58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd. 58

View Lastest Price from CASPASE INHIBITOR3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Asp(OMe)-fluoromethyl ketone pictures 2024-11-19 Boc-Asp(OMe)-fluoromethyl ketone
187389-53-3
 US $40.00-155.00 / mg ≥98% 10g TargetMol Chemicals Inc.

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CASPASE INHIBITOR3 (3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-pentanoic acid methyl ester N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone (S)-methyl 3-((tert-butoxycarbonyl)amino)-5-fluoro-4-oxopentanoate N-BOC-D-FMK Boc-D-FMK - Boc-Asp(OMe)-fluoromethyl ketone | BAF Pentanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-, methyl ester, (3S)- Boc-D-FMK/Boc-Asp(OMe)-fluoromethyl ketone inhibit,broad,Boc Asp(OMe) fluoromethyl ketone,Caspase,Fas-induced,Inhibitor,LDH,oxidative,apoptosis,spontaneous,BocAsp(OMe)fluoromethyl ketone,rupture Methyl (S)-3-((tert-butoxycarbonyl)amino)-5-fluoro-4-oxopentanoate 187389-53-3 C11H18NO5F Caspase/Related Products Apoptosis