5-Chloro-6-hydroxynicotinic Acid
- CAS No.
- 54127-63-8
- Chemical Name:
- 5-Chloro-6-hydroxynicotinic Acid
- Synonyms
- TIMTEC-BB SBB003814;Avatrombopag Impurity 53;Nicotinic Acid Impurity 16;oro-6-hydroxynicotinic Acid;5-CHLORO-6-HYDROXYNICOTINIC ACID;5-Chloro-6-hydroxynicotinicacid,98%;5-Chloro-6-hydroxynicotinic acid 98%;5-Chloro-6-hydroxynicotinic Acid >5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;3-CHLORO-2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID
- CBNumber:
- CB9399994
- Molecular Formula:
- C6H4ClNO3
- Molecular Weight:
- 173.55
- MDL Number:
- MFCD00052950
- MOL File:
- 54127-63-8.mol
- MSDS File:
- SDS
Melting point | ≥300 °C(lit.) |
---|---|
Boiling point | 334.6±42.0 °C(Predicted) |
Density | 1.4914 (rough estimate) |
refractive index | 1.5810 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
form | powder to crystal |
pka | 3.38±0.50(Predicted) |
color | White to Light yellow to Light orange |
CAS DataBase Reference | 54127-63-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37/38-20/21/22 | |||||||||
Safety Statements | 26-37/39-36 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 2933399990 | |||||||||
NFPA 704 |
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5-Chloro-6-hydroxynicotinic Acid price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | C1758 | 5-Chloro-6-hydroxynicotinic Acid >95.0%(GC)(T) | 54127-63-8 | 5g | $19 | 2024-03-01 | Buy |
Alfa Aesar | A15737 | 5-Chloro-6-hydroxynicotinic acid, 98% | 54127-63-8 | 5g | $40.65 | 2024-03-01 | Buy |
Alfa Aesar | A15737 | 5-Chloro-6-hydroxynicotinic acid, 98% | 54127-63-8 | 25g | $152.65 | 2024-03-01 | Buy |
TRC | C422058 | 5-Chloro-6-hydroxynicotinic Acid | 54127-63-8 | 100mg | $45 | 2021-12-16 | Buy |
TRC | C422058 | 5-Chloro-6-hydroxynicotinic Acid | 54127-63-8 | 500mg | $65 | 2021-12-16 | Buy |
5-Chloro-6-hydroxynicotinic Acid Chemical Properties,Uses,Production
Structure
5-Chloro-6-hydroxynicotinic Acid (5Cl6HNA) was recrystallized four times from ethanol at 345 K. The obtained white crystalline solid was first dried in a vacuum at 1.3 Pa and 353 K. The crystals were then ground with a mortar and a pestle and further dried for 24 h at 1.3 Pa and 353 K. The powder pattern obtained at 295 ± 1 K was indexed as monoclinic, space group P21/c, with a= 5.478 Å, b= 10.545 Å, c= 11.796 Å, β=97.76°. These results are in agreement with those obtained in this work from single crystal X-ray diffraction experiments carried out at 293 ±2K(P21/c, a ) 5.469 Å, b = 10.529 Å, c= 11.795 Å, β= 97.72°). DSC (fusion, β= 2 K ·min-1 ): Ton= 582.2 K and Tmax= 585.6 K[1].
Chemical Properties
white to beige fine crystalline powder
References
[1] Rui C. Santos. “Energetics and Structure of Hydroxynicotinic Acids. Crystal Structures of 2-, 4-, 6-Hydroxynicotinic and 5-Chloro-6-hydroxynicotinic Acids.” The Journal of Physical Chemistry B 113 43 (2009): 14291–14309.
5-Chloro-6-hydroxynicotinic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14394 | 58 |
Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2123 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from 5-Chloro-6-hydroxynicotinic Acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-02-19 | 5-chloro-6-hydroxynicotinic acid
54127-63-8
|
US $780.00 / g | 1g | 98 | 500 Kg | R&D Scientific Inc. | ||
2021-10-23 | 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid
54127-63-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | ||
2021-10-16 | 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid
54127-63-8
|
US $10.00 / KG | 1KG | 99% | 20 TONS | Hebei Zhanyao Biotechnology Co. Ltd |
- 5-chloro-6-hydroxynicotinic acid
54127-63-8
- US $780.00 / g
- 98
- R&D Scientific Inc.
- 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid
54127-63-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
- 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid
54127-63-8
- US $10.00 / KG
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
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