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Isoflupredone Acetate

CAS No.
338-98-7
Chemical Name:
Isoflupredone Acetate
Synonyms
predef;U-6013;biorinil;NSC 12600;NSC 37977;Predef R 2X;IsoflupredineAcetate;21-Acetoxy-9-fluoro-;Isoflupredone acetate;Nintedanib Impurity 156
CBNumber:
CB9500538
Molecular Formula:
C23H29FO6
Molecular Weight:
420.47
MDL Number:
MFCD00468096
MOL File:
338-98-7.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Isoflupredone Acetate Properties

Melting point 244-246° (dec)
alpha D23 +108° (c = 0.735 in dioxane)
Boiling point 576.5±50.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly)
pka 12.05±0.70(Predicted)
form Solid
color White to Off-White
FDA UNII 55P9TUL75S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
HS Code  2937220000

Isoflupredone Acetate price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I816610 IsoflupredoneAcetate 338-98-7 500mg $790 2021-12-16 Buy
American Custom Chemicals Corporation API0010029 ISOFLUPREDONE ACETATE 95.00% 338-98-7 1G $1871.1 2021-12-16 Buy
American Custom Chemicals Corporation API0010029 ISOFLUPREDONE ACETATE 95.00% 338-98-7 100MG $739.2 2021-12-16 Buy
Product number Packaging Price Buy
I816610 500mg $790 Buy
API0010029 1G $1871.1 Buy
API0010029 100MG $739.2 Buy

Isoflupredone Acetate Chemical Properties,Uses,Production

Uses

Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.

Definition

ChEBI: 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate is a corticosteroid hormone.

Veterinary Drugs and Treatments

Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids can be used for its antiinflammatory or immunosuppressive effects. Labeled indications for isoflupredone include: adjunctive treatment of bovine ketosis, alleviating pain and lameness associated with musculoskeletal conditions, acute hypersensitivity reactions, adjunctive treatment of overwhelming infections with severe toxicity, shock, supportive therapy in the treatment of stress conditions (e.g., surgery), dystocia, retained placenta, inflammatory ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce inflammation associated with recurrent airway obstruction (RAO, “heaves”, COPD).
While the drug could be used in small animals, it is recommended to use other glucocorticoid agents instead, where there has been more experience and other approved products for dogs and cats are available.

514-36-3
338-98-7
Synthesis of Isoflupredone Acetate from Fludrocortisone acetate
Global( 99)Suppliers
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Henan Fengda Chemical Co., Ltd
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View Lastest Price from Isoflupredone Acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isoflupredone Acetate pictures 2024-11-19 Isoflupredone Acetate
338-98-7
US $40.00-107.00 / mg 99.43% 10g TargetMol Chemicals Inc.
Isoflupredone Acetate pictures 2024-03-29 Isoflupredone Acetate
338-98-7
US $32.00-1.30 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Isoflupredone Acetate USP/EP/BP pictures 2021-07-16 Isoflupredone Acetate USP/EP/BP
338-98-7
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited

Isoflupredone Acetate Spectrum

4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-pregna-(11-be 4-diene-3,20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregna-21-acetate 9-alpha-fluoroprednisoloneacetate 9-fluoroprednisoloneacetate 9-fluorprednisoloneacetate biorinil predef ISOFLUPREDONE ACETATE (200 MG) isoflupredone 21-acetate 21-Acetoxy-9-fluoro-11,B-17-dihydroxy-pregna-1,4-diene-3,20-dione IsoflupredineAcetate 21-ACETOXY-9-FLUORO-11BETA,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11.beta.)- 21-acetoxy-9-fluoro-11,17-dihydroxy-pregna-1,4-diene-3,20-dione Isoflupredone acetate 21-ACETOXY-9-FLUORO-11SS,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE 21-(Acetyloxy)-9α-fluoro-11β,17α-dihyroxypregna-1,4-diene-3,20-dione U-6013 21-Acetoxy-9-fluoro- 9-Fluoroprednisolone-21-acetate NSC 12600 NSC 37977 Predef R 2X 2-((8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-diMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate Isoflupredone Acetate USP 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β)- Isoflupredone Acetate USP/EP/BP Isoflupredone Acetate (1348907) Isofluprednisone acetate 9-Fluoroprednisolone acetate(Isoflupredone acetate) 21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-dienen-3,20-dione Nintedanib Impurity 156 1, 4-PREGNADIEN-9α-FLUORO-11β, 17, 21-TRIOL-3, 20-DIONE 21-ACETATE 338-98-7 Intermediates & Fine Chemicals Pharmaceuticals Steroids