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1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one

CAS No.
16616-39-0
Chemical Name:
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
Synonyms
MLS-532223;MLS000532223;1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one;1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one;2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-;GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit
CBNumber:
CB96188330
Molecular Formula:
C15H9NO3
Molecular Weight:
251.24
MDL Number:
MFCD00560016
MOL File:
16616-39-0.mol
Last updated:2023-05-18 11:31:14

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Properties

Melting point 120-121 °C
Boiling point 419.6±47.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. RT (des.)
solubility Soluble in DMSO (up to 20 mg/ml).
form solid
color Beige
Stability Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0064006 MLS000532223 99.47% 16616-39-0 5mg $400 2021-12-16 Buy
ChemScene CS-0064006 MLS000532223 99.47% 16616-39-0 10mg $600 2021-12-16 Buy
ChemScene CS-0064006 MLS000532223 99.47% 16616-39-0 50mg $1800 2021-12-16 Buy
CSNpharm CSN27587 MLS000532223 16616-39-0 5mg $372 2021-12-16 Buy
CSNpharm CSN27587 MLS000532223 16616-39-0 50mg $1674 2021-12-16 Buy
Product number Packaging Price Buy
CS-0064006 5mg $400 Buy
CS-0064006 10mg $600 Buy
CS-0064006 50mg $1800 Buy
CSN27587 5mg $372 Buy
CSN27587 50mg $1674 Buy

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Chemical Properties,Uses,Production

Description

MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.

Definition

ChEBI: 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one is an aromatic compound.

References

1) Surviladze et al. (2010), Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay; J. Biomol. Screening, 15 10

645-00-1
201230-82-2
536-74-3
16616-39-0
Synthesis of 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one from 1-Iodo-3-nitrobenzene and carbon monoxide and Phenylacetylene

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3552 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8019 62
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shandong Jirun Biomedical Technology Co., Ltd. 0539-0539-8613587 17661611089 2639273505@qq.com China 164 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 2853979810@qq.com China 10049 58
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one MLS000532223 2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl- 1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one MLS-532223 GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit 16616-39-0