ALPHA1-ANTICHYMOTRYPSIN, HUMAN
- CAS No.
- 141176-92-3
- Chemical Name:
- ALPHA1-ANTICHYMOTRYPSIN, HUMAN
- Synonyms
- ACT;ALPHA-1-X;AACT, HUMAN;ANTI-AACT, HUMAN;ALPHA1-1X, HUMAN;ALPHA1-ACHY, HUMAN;α-Antichymotrypsin;ALPHA-1-X-GLYCOPROTEIN;ALPHA1-ANTICHYMOTRYPSIN;ALPHA-1X-GLYCOPROTEIN, HUMAN
- CBNumber:
- CB9738283
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00162030
- MOL File:
- Mol file
- MSDS File:
- SDS
| storage temp. | -20°C |
|---|---|
| form | lyophilized powder |
| NCI Dictionary of Cancer Terms | AC-T |
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 3 |
| HS Code | 3504009000 |
ALPHA1-ANTICHYMOTRYPSIN, HUMAN price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P3360 | Prostate Specific Antigen–α1-Antichymotrypsin Complex human ≥99%(SDS-PAGE),bufferedaqueoussolution | 141176-92-3 | 10μg | $741 | 2024-03-01 | Buy |
| Sigma-Aldrich | 178196 | α₁-Antichymotrypsin, Human Plasma - CAS 141176-92-3 - Calbiochem Acute-phase protein present at ~45 mg/100 ml in plasma. | 141176-92-3 | 100μg | $159 | 2024-03-01 | Buy |
| Sigma-Aldrich | A9285 | α1-Antichymotrypsin from human plasma ≥92.5% (SDS-PAGE), lyophilized powder | 141176-92-3 | 0.1mg | $213 | 2024-03-01 | Buy |
| Sigma-Aldrich | 178196 | α?-Antichymotrypsin, Human Plasma Acute-phase protein present at ~45 mg/100 ml in plasma. | 141176-92-3 | 1mg | $877 | 2024-03-01 | Buy |
| Apolloscientific | BITP1442 | Human Alpha-1 AntiChymotrypsin | 141176-92-3 | 20μg | $75 | 2021-12-16 | Buy |
ALPHA1-ANTICHYMOTRYPSIN, HUMAN Chemical Properties,Uses,Production
Uses
α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.
General Description
Kallikrein-3 (KLK3) or prostate specific antigen (PSA) is a serine protease. The protein contains a 371-residue N-terminal heavy chain, which is composed of four Apple domains. The PSA gene is localized to human chromosome 4q35. PSA is synthesized in the liver as a proenzyme known as prekallikrein. It is a key component of the kinin-generating pathways (PK system). The protein is involved in important physiological roles, such as blood pressure modulation, complement activation, and control and maintenance of inflammatory responses. KLK3b alleles are found to be associated with end-stage renal disease (ESRD) suggesting that variants in KLK3 gene might be linked with ESRD susceptibility.
SERPINA3 is also known as α-1-antichymotrypsin (ACT or AACT). The gene consists of five exons and is mapped to human chromosome 14q32.13. The protein contains 423 amino acids and belongs to the family of serpin superfamily of protease inhibitors. SERPINA3 inhibits the activity of pancreatic chymotrypsin, leukocyte, cathepsin G, mast cell chymases, human glandular, kallikrein 2 and kallikrein 3. Elevated expression of the protein has been observed in various types of carcinomas including breast carcinoma, hepatocellular carcinoma, prostate carcinoma and adenocarcinoma of the lung.
Biochem/physiol Actions
α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).
ALPHA1-ANTICHYMOTRYPSIN, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
ALPHA1-ANTICHYMOTRYPSIN, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29944 | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9844 | 58 |
| Suzhou Haiben Pharmaceutical Co., Ltd | 14760821013 13564957716 | 1816280386@qq.com | China | 7992 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6075 | 58 |
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