4-Cyclohexylphenol
- CAS No.
- 1131-60-8
- Chemical Name:
- 4-Cyclohexylphenol
- Synonyms
- CYCLOHEXYL PHENOL;4-Cyclohexyphenol;4-cyclohexyl-pheno;P-CYCLOHEXYLPHENOL;4-CYCLOHEXYLPHENOL;Of cyclohexyl phenol;CYCLOHEXYLPHENOL, 4-;Phenol, p-cyclohexyl-;PARA-CYCLOHEXYLPHENOL;Phenol, 4-cyclohexyl-
- CBNumber:
- CB9764431
- Molecular Formula:
- C12H16O
- Molecular Weight:
- 176.25
- MDL Number:
- MFCD00035699
- MOL File:
- 1131-60-8.mol
- MSDS File:
- SDS
| Melting point | 130-135°C |
|---|---|
| Boiling point | 213-215°C |
| Density | 0.9452 (rough estimate) |
| vapor pressure | 0.823-3.6Pa at 25℃ |
| refractive index | 1.5415 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 10.15±0.13(Predicted) |
| form | Solid:flakes |
| color | White to Light yellow to Light orange |
| Water Solubility | 66.66mg/L(25 ºC) |
| Dielectric constant | 4.0（54℃） |
| LogP | 4.22-4.33 |
| Indirect Additives used in Food Contact Substances | CYCLOHEXYLPHENOL, P- |
| FDA 21 CFR | 175.300 |
| CAS DataBase Reference | 1131-60-8(CAS DataBase Reference) |
| FDA UNII | M5536IXU6K |
| NIST Chemistry Reference | Phenol, 4-cyclohexyl-(1131-60-8) |
| EPA Substance Registry System | Phenol, 4-cyclohexyl- (1131-60-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Hazard Codes | Xi,N |
| Risk Statements | 20/21/22-36/37/38-50/53-41-37/38 |
| Safety Statements | 26-36/37/39-61-60-39 |
| Hazard Note | Irritant |
| HS Code | 2907199090 |
4-Cyclohexylphenol price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C0733 | 4-Cyclohexylphenol >98.0%(GC) | 1131-60-8 | 25g | $182 | 2024-03-01 | Buy |
| TRC | C992295 | 4-Cyclohexylphenol | 1131-60-8 | 5g | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC149862 | 4-Cyclohexylphenol | 1131-60-8 | 5G | $62.5 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2701-1-X8 | 4-Cyclohexylphenol 97% | 1131-60-8 | 25g | $32 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC149862 | 4-Cyclohexylphenol | 1131-60-8 | 2g | $50 | 2021-12-16 | Buy |
4-Cyclohexylphenol Chemical Properties,Uses,Production
Uses
4-Cyclohexylphenol is a derivative of Cyclohexylphenol (CHP), which is widely used in the preparation of dyes, resins, and biocides[2]. 4-Cyclohexylphenol labelled with 35s can be used for metabolic studies[3].
Synthesis
4-Cyclohexylphenol is obtained by hydroalkylation of phenol using phenol as a raw material in the presence of a palladium catalyst and a molten salt (NaCl-AlCl3)[1]. The specific synthesis steps are as follows:
The hydroalkylation of phenol in the presence of palladium catalyst and fused salt (NaCl-AlCl3) under hydrogen pressure was carried out. By using 1% Pd-Al2O3 (1 g) and the fused salt (1 : 1 mol ratio, 6 g), 4-cyclohexylphenol was obtained selectively from 1 (30 g) in a yield of 31.9% at 120°C for 4.5 h.
References
[1] T. KAMIYAMA; M. I; S Enomoto. Hydroalkylation of phenol to cyclohexylphenol in the presence of Pd-Al2O3 and NaCl-AlCl3 under hydrogen pressure.[J]. Chemical & pharmaceutical bulletin, 1986. DOI:10.1248/CPB.34.450.
[2] S. GUTIéRREZ-RUBIO . Synthesis of cyclohexylphenol via phenol hydroalkylation using Co2P/zeolite catalysts[J]. Catalysis Today, 2022. DOI:10.1016/j.cattod.2021.11.039.
[3] D.J. HEARSE; Gillian M P; A H Olavesen. The preparation and characterization of a series of 35S-labelled aryl sulphate esters for metabolic studies[J]. Biochemical pharmacology, 1969. DOI:10.1016/0006-2952(69)90022-7.
4-Cyclohexylphenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5857 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| Xingtai Haoxun Import and Export Trade Co., Ltd. | +8617733976525 | lisa@xthaoxun.com | CHINA | 249 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Hebei Runbin Biotechnology Co. LTD | 13180553332 | 2179877681@qq.com | CHINA | 990 | 58 |
View Lastest Price from 4-Cyclohexylphenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | 4-Cyclohexylphenol
1131-60-8
|
US $42.00-29.00 / mg | 99.93% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-18 | 4-Cyclohexylphenol
1131-60-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1000KG | Shaanxi Dideu New Materials Co. Ltd | |
 |
2024-10-25 | 4-Cyclohexylphenol
1131-60-8
|
US $0.00 / kg | 1kg | 0.99 | 20tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 4-Cyclohexylphenol
1131-60-8
- US $42.00-29.00 / mg
- 99.93%
- TargetMol Chemicals Inc.
-
- 4-Cyclohexylphenol
1131-60-8
- US $0.00-0.00 / KG
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-Cyclohexylphenol
1131-60-8
- US $0.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.