ChemicalBook >> CAS DataBase List >>3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
![3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Structure](CAS/20210111/GIF/1914989-80-2.gif)
- CAS No.
- 1914989-80-2
- Chemical Name:
- 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
- Synonyms
- Aβ42-IN-2;Aβ42-IN-2;Aβ42 IN 2,Aβ42IN2;3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
- CBNumber:
- CB98188264
- Molecular Formula:
- C24H26N6O2
- Molecular Weight:
- 430.5
- MDL Number:
- MFCD32857167
- MOL File:
- 1914989-80-2.mol
Last updated:2024-07-02 08:55:42
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Properties
| Boiling point | 651.4±55.0 °C(Predicted) |
|---|---|
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, stored under nitrogen |
| solubility | DMSO : 20 mg/mL (46.46 mM; Need ultrasonic) |
| pka | 4.22±0.10(Predicted) |
| form | Solid |
| color | Off-white to light yellow |
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0134166 | Aβ42-IN-2 98.14% | 1914989-80-2 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0134166 | Aβ42-IN-2 98.14% | 1914989-80-2 | 10mg | $580 | 2021-12-16 | Buy |
| ChemScene | CS-0134166 | Aβ42-IN-2 98.14% | 1914989-80-2 | 50mg | $1650 | 2021-12-16 | Buy |
| ChemScene | CS-0134166 | Aβ42-IN-2 98.14% | 1914989-80-2 | 100mg | $2550 | 2021-12-16 | Buy |
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Chemical Properties,Uses,Production
Biological Activity
Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for αβ42. Aβ42-IN-2 can be used for the research of Alzheimer’s disease[1].
References
[1]. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1.
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Preparation Products And Raw materials
Raw materials
Preparation Products
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9274 | 58 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| RD International Technology Co., Limited | 58 |
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Spectrum
3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl-
Aβ42-IN-2
Aβ42 IN 2,Aβ42IN2
Aβ42-IN-2
1914989-80-2