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Epitiostanol

CAS No.
2363-58-8
Chemical Name:
Epitiostanol
Synonyms
10275S;Thiodrol;NSC 194684;Epitiostano;Epitiostanol;EPitostsanol;Epithiostanol;Epitiostanol RS;Epithioandrostanol;Epitiostanol USP/EP/BP
CBNumber:
CB9875137
Molecular Formula:
C19H30OS
Molecular Weight:
306.51
MDL Number:
MFCD00866499
MOL File:
2363-58-8.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:58

Epitiostanol Properties

Melting point 127-128°
alpha D27.5 +24.4° (c = 1.054 in chloroform)
Boiling point 417.1°C (rough estimate)
Density 1.0122 (rough estimate)
refractive index 1.5700 (estimate)
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 15.10±0.60(Predicted)
color White to Off-White
Water Solubility 1.2mg/L(37 ºC)
FDA UNII YE7586973L

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice, rats (mg/kg): 1, 5 i.p. (Minesita, p 805)

Epitiostanol Chemical Properties,Uses,Production

Originator

Thiodrol,Shionogi,Japan,1977

Uses

An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.

Definition

ChEBI: Epitiostanol is an organic molecular entity.

Manufacturing Process

A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17- acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while stirring. To the reaction mixture, there is added water, and the separated substance is collected by filtration and crystallized from hexane to give 2β,3β- epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at 132.5°C to 134°C.

Therapeutic Function

Antineoplastic

Epitiostanol Preparation Products And Raw materials

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29814 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60
Chizhou Kailong Import and Export Trade Co., Ltd. xg01_gj@163.com China 9484 50
Raw material medicin reagent co.,Ltd sales@njromanme.com China 4529 58
Wuhan Yanzhe Technology Co., Ltd 15527250409 wenhaotian12@163.com China 4495 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44918 58

View Lastest Price from Epitiostanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Epitiostanol pictures 2020-02-13 Epitiostanol
2363-58-8
US $1.00 / KG 1KG Min98% HPLC g/kg/ton Career Henan Chemical Co
  • Epitiostanol pictures
  • Epitiostanol
    2363-58-8
  • US $1.00 / KG
  • Min98% HPLC
  • Career Henan Chemical Co
2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol Epithioandrostanol Epitiostanol 10275S 2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstan-17-ol deriv. 2α,3α-Epithio-5α-androstan-17β-ol 5α-Androstan-17β-ol, 2α,3α-epithio- (7CI, 8CI) Androstan-17-ol, 2,3-epithio-, (2α,3α,5α,17β)- Epithiostanol NSC 194684 Thiodrol 2,3-Epithio-1H-cyclopenta[a]phenanthrene (2α,3α,5α,17β)-2,3-Epithioandrostan-17-ol Androstan-17-ol,2,3-epithio-, (2a,3a,5a,17b)- Epitiostano EPitostsanol Epitiostanol (Contains up to 15% 3α,4α-Epithioandrostan Isomer) Epitiostanol RS Epitiostanol USP/EP/BP 2363-58-8 C19H30OS Inhiitors Intermediates & Fine Chemicals Pharmaceuticals Steroids Sulfur & Selenium Compounds