butaperazine
- CAS No.
- 653-03-2
- Chemical Name:
- butaperazine
- Synonyms
- AHR-712;Riker-595;Bayer-1362;Butaperazina;butaperazine;Butyrylperazine;Butyrylyperazine;1-[10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazin-2-yl]butan-1-one;1-[10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazin-2-yl]-1-butanone;1-Butanone, 1-[10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazin-2-yl]-
- CBNumber:
- CB9902301
- Molecular Formula:
- C24H31N3OS
- Molecular Weight:
- 409.59
- MDL Number:
- MFCD00242848
- MOL File:
- 653-03-2.mol
| Boiling point | bp0.05 270-280° |
|---|---|
| Density | 1.138±0.06 g/cm3(Predicted) |
| pka | 7.66±0.10(Predicted) |
| FDA UNII | TXP4T9106S |
| ATC code | N05AB09 |
butaperazine Chemical Properties,Uses,Production
Originator
Bayer 1362,Bayer
Uses
Antipsychotic.
Definition
ChEBI: Butaperazine is a member of phenothiazines.
Manufacturing Process
To a suspension of sodamide in liquid ammonia is added of 2-
buterylphenothiazine. After stirring for one hour, there is added 1-bromo-3-
chloropropane. The ammonia is allowed to evaporate and the residue is
diluted with the water. The mixture is extracted with ether and the ether
solution is dried over anhydrous sodium sulfate, filtered and concentrated. The
residue consists of crude 10-(3-chloropropyl)-2-buterylphenothiazine as
viscous oil and is used in the next step without further purification.
A mixture of 1-methylpiperazine and crude 10-(3-chloropropyl)-2-
buterylphenothiazine is heated on a steam bath for 18 hours. The mixture is
diluted with the water and extracted with ether. The ether solution is
extracted with dilute hydrochloric acid. The aqueous acid solution is made
alkaline with sodium hydroxide and the product is extracted with ether. The
ether extracts are dried and concentrated to a residue consisting of the free
base 2-butyryl-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine.
Therapeutic Function
Neuroleptic, Antiemetic
butaperazine Preparation Products And Raw materials
Raw materials
Preparation Products
butaperazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9020 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55936 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |