2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
![2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride Structure](CAS/20180906/GIF/41544-24-5.gif)
- CAS No.
- 41544-24-5
- Chemical Name:
- 2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
- Synonyms
- Virumerz;Viruserol;Viru-merz;Einecs 255-434-5;Tromantadine HCl;Tromantadin hydrochlorid;2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride
- CBNumber:
- CB9919691
- Molecular Formula:
- C16H28N2O2.ClH
- Molecular Weight:
- 316.86666
- MDL Number:
- MOL File:
- 41544-24-5.mol
- MSDS File:
- SDS
| Melting point | 157-158° |
|---|---|
| form | Solid |
| color | White to off-white |
| FDA UNII | H09LUS437B |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 orally in rats: 630 mg/kg; i.v. in mice: 71.0 mg/kg (Peteri, Sterner) |
|---|
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0116392 | Tromantadinehydrochloride ≥98.0% | 41544-24-5 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0116392 | Tromantadinehydrochloride ≥98.0% | 41544-24-5 | 10mg | $580 | 2021-12-16 | Buy |
| ChemScene | CS-0116392 | Tromantadinehydrochloride ≥98.0% | 41544-24-5 | 50mg | $1650 | 2021-12-16 | Buy |
| ChemScene | CS-0116392 | Tromantadinehydrochloride ≥98.0% | 41544-24-5 | 100mg | $2550 | 2021-12-16 | Buy |
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride Chemical Properties,Uses,Production
Originator
Viru-Merz,Merz,W. Germany,1973
Manufacturing Process
Adamantane is first reacted with chloroacetyl chloride to give
chloroacetylaminoadamantane.
2.3 g Na (0.1 g-atom) were dissolved in 75 ml dimethylamino-ethanol. Then
the excess alcohol was distilled off completely and the sodium salt developed
was dried in a vacuum. After drying, the salt was dissolved in about 200 ml
xylene. To thissolution.22.8 g (0.1 mol) chloroacetylaminoadamantane were added, heated for 10 hours under reflux in a 250-ml round-bottomed flask
with a reflux cooler, and the sodium chloride developed subsequently filtered
off.
Next the xylene was distilled away, the liquid residue dissolved in about 80 ml
carbon tetrachloride and the hydrochloride precipitated through introduction of
hydrochloric acid gas. The hydrochloride was dissolved in about 100 ml
acetone and the solvent subsequently distilled away, whereby excess
hydrochloric acid passed over with it. This operation was repeated until no
excess acid was present.
A large excess of petroleum ether was added in a 500 ml three-necked flask
provided with a stirrer and reflux cooler, to a concentrated acetonic solution of
the hydrochloride and stirred for at least 1 hour, whereby the desired
substance was deposited in a crystalline form. Finally, the substance was
filtered away and dried in a desiccator. 14 g of the substance (15% of theory)
were obtained.
Therapeutic Function
Antiviral
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride Preparation Products And Raw materials
2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10011 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
View Lastest Price from 2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Tromantadine hydrochloride
41544-24-5
|
US $332.00-1360.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Tromantadine hydrochloride
41544-24-5
- US $332.00-1360.00 / mg
- TargetMol Chemicals Inc.