2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride

2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride C화학적 특성, 용도, 생산

Originator

Viru-Merz,Merz,W. Germany,1973

Manufacturing Process

Adamantane is first reacted with chloroacetyl chloride to give chloroacetylaminoadamantane. 2.3 g Na (0.1 g-atom) were dissolved in 75 ml dimethylamino-ethanol. Then the excess alcohol was distilled off completely and the sodium salt developed was dried in a vacuum. After drying, the salt was dissolved in about 200 ml xylene. To thissolution.22.8 g (0.1 mol) chloroacetylaminoadamantane were added, heated for 10 hours under reflux in a 250-ml round-bottomed flask with a reflux cooler, and the sodium chloride developed subsequently filtered off.
Next the xylene was distilled away, the liquid residue dissolved in about 80 ml carbon tetrachloride and the hydrochloride precipitated through introduction of hydrochloric acid gas. The hydrochloride was dissolved in about 100 ml acetone and the solvent subsequently distilled away, whereby excess hydrochloric acid passed over with it. This operation was repeated until no excess acid was present.
A large excess of petroleum ether was added in a 500 ml three-necked flask provided with a stirrer and reflux cooler, to a concentrated acetonic solution of the hydrochloride and stirred for at least 1 hour, whereby the desired substance was deposited in a crystalline form. Finally, the substance was filtered away and dried in a desiccator. 14 g of the substance (15% of theory) were obtained.

Therapeutic Function

Antiviral

2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride 준비 용품 및 원자재

원자재

준비 용품

2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-ylacetamide monohydrochloride 공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3460	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 18892239720	psaitong@jm-bio.com	China	12308	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
cjbscvictory	13348960310 13348960310	3003867561@qq.com	China	10011	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 15801484223;	psaitong@jm-bio.com	China	29778	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9282	58