Coenzyme Q10
- CAS No.
- 303-98-0
- Chemical Name:
- Coenzyme Q10
- Synonyms
- COENZYME Q10;COQ10;UBIQUINONE;coenzyme Q10 synthetic;UBIQUINONE-10;Conzyme Q10;Q10 COENZYME;Coenzyme Q10 Powder;CoQ10 Ubidecarenone;CoenzymeQ10Ubidecarenone
- CBNumber:
- CB0121840
- Molecular Formula:
- C59H90O4
- Molecular Weight:
- 863.34
- MOL File:
- 303-98-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 49-51 °C |
|---|---|
| Boiling point | 715.32°C (rough estimate) |
| Density | 0.9145 (rough estimate) |
| refractive index | 1.4760 (estimate) |
| storage temp. | -20°C |
| solubility | Soluble in chloroform. |
| form | Solid |
| color | Light Orange to Dark Orange |
| Sensitive | Light Sensitive |
| Merck | 14,9843 |
| BRN | 1900141 |
| Stability | Stable, but may be light or heat sensitive. Store in the dark at -20 C. Incompatible with strong oxidizing agents. |
| InChIKey | ACTIUHUUMQJHFO-DQXDOXBUSA-N |
| LogP | 19.119 (est) |
| CAS DataBase Reference | 303-98-0(CAS DataBase Reference) |
| EPA Substance Registry System | Ubidecarenone (303-98-0) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DK3900000 | |||||||||
| F | 8-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29146990 | |||||||||
| Toxicity | LD50 intramuscular in mouse: > 500mg/kg | |||||||||
| NFPA 704 |
|
Coenzyme Q10 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C9538 | Coenzyme Q10 ≥98% (HPLC) | 303-98-0 | 100MG | ₹7566.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1929 | Ubidecarenone Pharmaceutical Secondary Standard; Certified Reference Material | 303-98-0 | 500MG | ₹23739.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C9538 | Coenzyme Q10 ≥98% (HPLC) | 303-98-0 | 500MG | ₹29270.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C9538 | Coenzyme Q10 ≥98% (HPLC) | 303-98-0 | 1G | ₹40853.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 07386 | Coenzyme Q10 analytical standard | 303-98-0 | 10MG | ₹8465.15 | 2022-06-14 | Buy |
Coenzyme Q10 Chemical Properties,Uses,Production
Chemical Properties
Yellow-Orange Crystalline Powder
Occurrence
Coenzyme Q10 is found in dietary sources. Coenzyme Qmolecules have side chains of differentlengths in different types of organismsbut function in similar ways.
Uses
Ubidecarenone is also known as coenzyme Q10 it is a powerful antioxidant that is naturally found in the cells. It acts as a free radical neutraliser.
Definition
ChEBI: Coenzyme Q10 is a ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration. It has a role as a human metabolite, a ferroptosis inhibitor and an antioxidant. It is found in animal organs and yeast with active in the citric acid cycle in carbohydrate metabolism.
General Description
Ubidecarenone, referred to as coenzyme Q, is abundantly available in human cells, with major proportions being present in vital body organs such as heart and kidneys. It plays an important role in cell metabolism owing to its significant contribution to the electron transport pathway. It is a strong antioxidant and acts as an essential enzyme catalyst in mitochondrial oxidative phosphorylation.
Biological Activity
Component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Displays neuroprotective activity.
Side effects
Mild side effects might include digestive problems such as:
Upper abdominal pain; Loss of appetite; Nausea and vomiting; Diarrhea.
Other possible side effects may include:
Headaches and dizziness; Insomnia; Fatigue; Skin itching or rashes; Irritability or agitation.
Drug interactions
Coenzyme Q10 supplements may interact with some antihypertensive (those that lower blood pressure) and chemotherapy drugs. Coenzyme Q10 may increase the risk of blood clots in people who take the anticoagulant warfarin by decreasing warfarin's effectiveness.
Purification Methods
Purify it by recrystallisation from EtOH, EtOH/Me2CO or Et2O/EtOH and by chromatography on silica gel using isoPrOH/Et2O (3:1) to give orange crystals. It has max 270nm ( 15,170) in pet ether. [Terao et al. J Org Chem 44 868 1979, NMR and MS: Naruta et al. J Org Chem 45 4097 1980, IR: Lester et al. Biochem Biophys Acta 42 1278 1959, NMR: Planta et al. Helv Chim Acta 42 1278 1959; Morton Biochemical Spectroscopy (Adam Hilger, London, 1975) p 491].
Coenzyme Q10 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Medi Pharma Drug House | +919930911911 | Mumbai, India | 143 | 58 | Inquiry |
| Meteoric Biopharmaceuticals Pvt. Ltd. | +91-8511121361 +91-8511121361 | Mumbai, India | 71 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Besil Chem LLP | +91-7760252666 +91-9880731835 | Bangalore, India | 163 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Bio Gen Extracts Pvt Ltd | +91-7022903130 +91-9108058822 | Karnataka, India | 11 | 58 | Inquiry |
| Symbio Generrics (I) Pvt Ltd | +91-8121318328 +91-9099033709 | Karnataka, India | 22 | 58 | Inquiry |
| Apionex Pharma Pvt Ltd | +91-9773830459 +91-9819236256 | Maharashtra, India | 26 | 58 | Inquiry |
| Beloorbayir Biotech Ltd | +91-8792661159 +91-8867683718 | Karnataka, India | 25 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
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