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6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE

6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE Structure
CAS No.
199934-16-2
Chemical Name:
6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE
Synonyms
UCL 1684;UCL-1684 Br;UCL 1684 dibromide;6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,;6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diiumdibromide;6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE
CBNumber:
CB0145884
Molecular Formula:
C38H30F6N4O4
Molecular Weight:
720.66
MOL File:
199934-16-2.mol
Modify Date:
2023/6/30 15:45:59
Request For Quotation

6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE Properties

storage temp. Desiccate at RT
solubility DMSO: 10 mg/mL
form Powder
color white to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE Chemical Properties,Uses,Production

Uses

UCL 1684 is a highly potent and selective, nonpeptidic blocker of the Apamin-sensitive Ca2+-activated K+ channel of which inhibition potentially terminates and protects against atrial fibrillation.

Biological Activity

Highly potent, non-peptidic blocker of the apamin-sensitive Ca 2+ -activated K + channel (SK Ca ) (IC 50 = 3 nM in rat sympathetic neurons). Blocks hSK1 and rSK2 channels expressed in HEK 293 cells with IC 50 values of 762 and 364 pM respectively.

6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE Suppliers

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199934-16-2(6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE)Related Search:

Pyridine trifluoroacetate AMMONIUM FLUOROACETATE 6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE
6,12,19,20,25,26-HEXAHYDRO-5,27:13,18:21,24-TRIETHENO-11,7-METHENO-7H-DIBENZO [B,N] [1,5,12,16]TETRAAZACYCLOTRICOSINE-5,13-DIIUM DITRIFLUOROACETATE UCL 1684 6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5, 6,12,19,20,25,26-Hexahydro-5,27:13,18:21,24-trietheno-11,7-metheno-7H-dibenzo[b,n][1,5,12,16]tetraazacyclotricosine-5,13-diiumdibromide UCL-1684 Br UCL 1684 dibromide 199934-16-2 C34H30Br2N4 C34H30N42C2F3O2 Potassium Channel Modulators Monovalent Ion Channels Ion Channels Voltage-gated Ion Channels Cell Biology Cell Signaling and Neuroscience BioChemical