ChemicalBook > Product Catalog >Biochemical Engineering >Chinese Herbs >Theaflavin 3,3′-digallate

Theaflavin 3,3′-digallate

CAS No.: 30462-35-2

Chemical Name:: Theaflavin 3,3′-digallate

Synonyms: TFDG;theaflavin 3;8-Gingerol Hplc;8-GINGEROL, HPLC 98%;Theaflavin 3,3’THEAFLAVIN 3,3'-DIGALLATE;Theaflavin 3,3'-digallate;THEAFLAVIN 3,3'-DI-O-GALLATE;Theaflavin 3,3'-di-O-gallate;Theaflavin-3,3-digallate(TF3)

CBNumber:: CB0156596

Molecular Formula:: C43H32O20

Molecular Weight:: 868.71

MOL File:: 30462-35-2.mol

Modify Date:: 2024/7/2 8:54:57

Request For Quotation

Theaflavin 3,3′-digallate Properties

Melting point	226～230℃
Boiling point	1352.6±65.0 °C(Predicted)
Density	1.97±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C, sealed storage, away from moisture and light
solubility	DMSO : 41.67 mg/mL (47.97 mM; Need ultrasonic)
form	Solid
pka	6.55±0.20(Predicted)
color	Red-purple
InChIKey	ZEASWHWETFMWCV-ISBUVJFSSA-N
CAS DataBase Reference	30462-35-2

SAFETY

Risk and Safety Statements

WGK Germany	3
HS Code	29329990

Theaflavin 3,3′-digallate Chemical Properties,Uses,Production

Description

Theaflavin-3,3''-digallate (TFDG) is a major polyphenol found in black tea with diverse biological activities. It has antioxidant activity, inhibiting the formation of superoxide radicals, singlet oxygen, hydrogen peroxide, and hydroxyl radicals in vitro (IC₅₀s = 26.7, 0.83, 0.39, and 25.07 μmol/L, respectively). It also reduces hydroxyl radical-induced damage to plasmid DNA. TFDG (12.5-50 μM) prevents LPS-induced release of TNF-α, IL-1β, and IL-6, expression of JNK and p38, and nuclear translocation of NF-κB in RAW 264.7 cells. In vivo, TFDG reduces serum levels of TNF-α, IL-1β, and IL-6 and decreases pulmonary edema, pulmonary congestion, and thickening of the alveolar wall in a mouse model of LPS-induced acute lung injury. It also inhibits osteoclast formation, polarization, and osteoclastic bone resorption in vitro and reduces titanium particle-induced bone erosion and the number of mature osteoclasts in mice in a dose-dependent manner.

Uses

Theaflavin 3,3''-Digallate has been found to be an inhibitor against human pancreatic α-Amylase.

Theaflavin 3,3′-digallate Preparation Products And Raw materials

Raw materials

Preparation Products

Theaflavin 3,3′-digallate Suppliers

Global( 148)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9337	55	Inquiry
Chengdu Greenpure Biopharma CO.,Ltd	18283602253; +8618283602253	China	952	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29898	58	Inquiry
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	CHINA	1824	58	Inquiry
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	China	3777	58	Inquiry
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	China	3000	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
Hubei Ipure Biology Co., Ltd	+8613367258412	China	10326	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Hangzhou FandaChem Co.,Ltd.	55
Chengdu Greenpure Biopharma CO.,Ltd	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Shaanxi Pioneer Biotech Co., Ltd .	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Hubei Ipure Biology Co., Ltd	58

Theaflavin 3,3'-digallate – a polyphenol in black tea
Theaflavin-3,3'-digallate (TFDG) is a major polyphenol found in black tea with diverse biological activities. It has antioxida....
Dec 23，2019

30462-35-2(Theaflavin 3,3′-digallate)Related Search:

6-GINGEROL,[6]-GINGEROL, ZINGIBER OFFICINALE Propyl gallate Theaflavin Methyl gallate THEAFLAVIN 3'-O-GALLATE

1,3,6-TRI-O-GALLOYL-B-D-GLUCOSE (-)-Epigallocatechin Punicalagin (-)-EGCG-3''-O-ME 6-Shogaol

8-O-acetyl shanzhiside methyl ester YUNACONITINE lithospermic acid THEAFLAVINE-3-GALLATE THEAFLAVINE-3,3'-DIGALLATE

10-GINGEROL (-)-Epicatechin gallate cis-(±)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol

chevron_left

1of4

chevron_right

theaflavin 3 THEAFLAVIN 3,3'-DIGALLATE THEAFLAVIN 3,3'-DI-O-GALLATE 3,4,5-Trihydroxybenzoic acid (3,4,6-trihydroxy-5-oxo-5H-benzocycloheptene-1,8-diyl)bis[(2R,3R)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-2,3-diyl] ester 8-GINGEROL, HPLC 98% 3,4,6-Trihydroxy-1,8-bis[[(2R)-3,4-dihydro-3α-(3,4,5-trihydroxybenzoyloxy)-5,7-dihydroxy-2H-1-benzopyran]-2α-yl]-5H-benzocycloheptene-5-one 3,4,6-Trihydroxy-1,8-bis[[(2R)-3,4-dihydro-5,7-dihydroxy-3α-(3,4,5-trihydroxybenzoyloxy)-2H-1-benzopyran]-2α-yl]-5H-benzocycloheptene-5-one 8-Gingerol Hplc [(2R,3R)-2-[1-[(2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,5-trihydroxy-6-oxobenzo[7]annulen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate Theaflavin-3,3-digallate(TF3) TFDG Theaflavin 3,3&rsquo Benzoic acid, 3,4,5-trihydroxy-, 1,1'-[(3,4,6-trihydroxy-5-oxo-5H-benzocycloheptene-1,8-diyl)bis[(2R,3R)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-2,3-diyl]] ester Theaflavin 3,3'-digallate USP/EP/BP TheaflAVin-3-3’-digallateQ: What is TheaflAVin-3-3’-digallate Q: What is the CAS Number of TheaflAVin-3-3’-digallate Q: What is the storage condition of TheaflAVin-3-3’-digallate Q: What are the applications of TheaflAVin-3-3’-digallate [(2R,3R)-3-[1-[5,7-dihydroxy-2-(3,4,5-trihydroxybenzoyl)oxy-chroman-3-yl]-3,4,6-trihydroxy-5-oxo-benzo[7]annulen-8-yl]-5,7-dihydroxy-chroman-2-yl] 3,4,5-trihydroxybenzoate Theaflavin 3,3'-digallate Theaflavin 3,3'-di-O-gallate 30462-35-2 C43H32O20 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract The group of Ginerols Miscellaneous Natural Products