AC-YVAD-CMK
- CAS No.
- 178603-78-6
- Chemical Name:
- AC-YVAD-CMK
- Synonyms
- AC-YVAD-CMK;ICE INHIBITOR II;AC-TYR-VAL-ALA-ASP-CMK;CASPASE-1 INHIBITOR II;AC-TYR-VAL-ALA-ASP-CH2CL;N-Ac-Tyr-Val-Ala-Asp-CMK;5-Trihydroxybenzoic acid;Ac-YVAD-cmk >=95% (HPLC);AC-YVAD-CHLOROMETHYLKETONE;AC-TYR-ALA-ASP-CHLOROMETHYLKETONE
- CBNumber:
- CB0168634
- Molecular Formula:
- C24H33ClN4O8
- Molecular Weight:
- 540.99
- MOL File:
- 178603-78-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:20
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
AC-YVAD-CMK price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0429 | Ac-YVAD-cmk ≥95% (HPLC) | 178603-78-6 | 1MG | ₹10727.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0429 | Ac-YVAD-cmk ≥95% (HPLC) | 178603-78-6 | 5MG | ₹43830.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 400012 | Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem The Caspase-1 Inhibitor II, also referenced under CAS 178603-78-6, controls the biological activity of Caspase-1. This small molecule/inhibitor is pri | 178603-78-6 | 5MG | ₹37040 | 2022-06-14 | Buy |
AC-YVAD-CMK Chemical Properties,Uses,Production
Uses
Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Ac-YVAD-CMK is neuroprotective in a rat model of cerebral ischemia.[Cayman Chemical]
General Description
Interleukin-1β converting enzyme (ICE) is a cysteine protease that cleaves the IL-1β precursor to mature IL-1β. Caspase-1 inhibitor II is a cell-permeable, irreversible inhibitor of Caspase-1, Caspase-4, and Caspase-5. Inhibits CPP32/Apopain at a much higher concentration. Inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation.
Biochem/physiol Actions
Ac-YVAD-cmk is a selective ireversible inhibitor of caspase-1 (interleukin-1β converting enzyme, ICE) with some activity also against caspase-4. Ac-YVAD-cmk is anti-apoptotic and has anti-inflammatory and neuroprotective effects, thought to result from its preventing caspase-1 activation of the proinflammatory cytokine, Interleukin-1β.
AC-YVAD-CMK Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 118)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
| Nanjing TGpeptide | +86-13347807150 +86-13347807150 | China | 3279 | 58 | Inquiry |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | China | 2944 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| DONBOO AMINO ACID COMPANY | +8613063595538 | China | 9365 | 58 | Inquiry |
178603-78-6(AC-YVAD-CMK)Related Search:
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ICE INHIBITOR II
IL-1BETA CONVERTING ENZYME (ICE) INHIBITOR II
IL-1BETA CONVERTING ENZYME INHIBITOR II
INTERLEUKIN-1BETA (IL-1BETA) CONVERTING ENZYME (ICE) INHIBITOR II
CASPASE-1 INHIBITOR (CHLOROMETHYLKETONE)
AC-TYR-ALA-ASP-CHLOROMETHYLKETONE
AC-TYR-VAL-ALA-ASP-CH2CL
AC-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE
AC-TYR-VAL-ALA-ASP-CMK
AC-YVAD-CHLOROMETHYLKETONE
AC-YVAD-CMK
(ACETYL-L-TYROSYL-L-VALYL-L-ALANYL-L-ASPART-1-YL)CHLOROMETHANE
N-ACETYL-TYR-VAL-ALA-ASP CHLOROMETHYL KETONE
N-ACETYL-L-TYROSYL-L-VALYL-N-[(1S)-1-(CARBOXYMETHYL)-3-CHLORO-2-OXOPROPYL]-L-ALANINAMIDE
interleukin-1B (1L-1B) converting*enzyme (ice) in
N-ACETYL-TYR-VAL-ALA-ASP CHLOROMETHYL KE
interleukin-1β (il-1β) converting enzyme (ice) inhibitor ii
INTERLEUKIN-1BETA CONVERTING ENZYME INHIBITOR II
N-Ac-Tyr-Val-Ala-Asp-CMK
AC-TYR-VAL-ALA-ASP-CMK ; AC-YVKD-CMK
CASPASE-1 INHIBITOR II
CASPASE 1 INHIBITOR II;AC-YVAD-CMK
Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem
L-Alaninamide, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-
(4S,7S,10S,13S)-13-(2-Chloroacetyl)-4-(4-hydroxybenzyl)-7-isopropyl-10-methyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
5-Trihydroxybenzoic acid
Ac-YVAD-cmk >=95% (HPLC)
178603-78-6
C24H33ClN4O8
BioChemical
Apoptosis and Cell Cycle
Cell Signaling and Neuroscience
Caspase 1
Caspases
Cell Biology
Inhibitors
Caspase/Related Products
peptide
Pepetides
peptides
Elisa Kit-Mouse Elisa Kit