AMASTATIN HYDROCHLORIDE
- CAS No.
- 100938-10-1
- Chemical Name:
- AMASTATIN HYDROCHLORIDE
- Synonyms
- AMASTATIN;AMASTATIN HCL;AMASTATIN HYDROCHLORIDE;AMASTATIN HYDROCHLORIDE HYDRATE;H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL;Amastatin hydrate hydrochloride;4-formylphenyl-O-β-d-allopyranoside;N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&;Amastatinhydrochloridebiochemikasynthetic;(2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL
- CBNumber:
- CB0194817
- Molecular Formula:
- C21H39ClN4O8
- Molecular Weight:
- 511.01
- MOL File:
- 100938-10-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/20 18:13:44
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P271-P261-P280 |
WGK Germany | 3 |
F | 10 |
HS Code | 2924190090 |
AMASTATIN HYDROCHLORIDE price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A1276 | Amastatin hydrochloride hydrate ≥97% (HPLC) | 100938-10-1 | 0.5MG | ₹12524.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1276 | Amastatin hydrochloride hydrate ≥97% (HPLC) | 100938-10-1 | 1MG | ₹20892.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1276 | Amastatin hydrochloride hydrate ≥97% (HPLC) | 100938-10-1 | 5MG | ₹69756.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1276 | Amastatin hydrochloride hydrate ≥97% (HPLC) | 100938-10-1 | 10MG | ₹124963.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A1276 | Amastatin hydrochloride hydrate ≥97% (HPLC) | 100938-10-1 | 25MG | ₹230789 | 2022-06-14 | Buy |
AMASTATIN HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 μg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 μM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.[Cayman Chemical]
General Description
Chemical structure: peptide
Biochem/physiol Actions
It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.
AMASTATIN HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15438 | 58 | Inquiry |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | China | 888 | 58 | Inquiry |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 | China | 3279 | 58 | Inquiry |
LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |