AMASTATIN HYDROCHLORIDE

AMASTATIN HYDROCHLORIDE Structure
CAS No.
100938-10-1
Chemical Name:
AMASTATIN HYDROCHLORIDE
Synonyms
AMASTATIN;AMASTATIN HCL;AMASTATIN HYDROCHLORIDE;AMASTATIN HYDROCHLORIDE HYDRATE;H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL;Amastatin hydrate hydrochloride;4-formylphenyl-O-β-d-allopyranoside;N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&;Amastatinhydrochloridebiochemikasynthetic;(2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL
CBNumber:
CB0194817
Molecular Formula:
C21H39ClN4O8
Molecular Weight:
511.01
MOL File:
100938-10-1.mol
MSDS File:
SDS
Modify Date:
2024/5/20 18:13:44

AMASTATIN HYDROCHLORIDE Properties

Melting point 202-205 °C
storage temp. -20°C
solubility methanol: 5 mg/mL, clear, colorless
form White to off-white powder.
color White to off-white
BRN 8888370

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
WGK Germany  3
10
HS Code  2924190090

AMASTATIN HYDROCHLORIDE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 100938-10-1 0.5MG ₹12524.53 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 100938-10-1 1MG ₹20892.25 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 100938-10-1 5MG ₹69756.3 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 100938-10-1 10MG ₹124963.8 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 100938-10-1 25MG ₹230789 2022-06-14 Buy
Product number Packaging Price Buy
A1276 0.5MG ₹12524.53 Buy
A1276 1MG ₹20892.25 Buy
A1276 5MG ₹69756.3 Buy
A1276 10MG ₹124963.8 Buy
A1276 25MG ₹230789 Buy

AMASTATIN HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 μg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 μM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.[Cayman Chemical]

General Description

Chemical structure: peptide

Biochem/physiol Actions

It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.

AMASTATIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 101)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Hebei Duling International Trade Co. LTD +8617333973358 China 15438 58 Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Nanjing TGpeptide +86-13347807150 +86-13347807150 China 3279 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
[(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP HYDROCHLORIDE (2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL AMASTATIN HYDROCHLORIDE AMASTATIN HYDROCHLORIDE HYDRATE H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L& Amastatinhydrochloridebiochemikasynthetic (2s,3r)-3-amino-2-hydroxy-5-methylhexanoyl-val-val-asp hydrochloride hydrate (Amino-2-hydroxy-5-methyl-hexanoyl)-L-valyl-L-valyl-L-aspartic acid hydrochloride salt (2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrate hydrochloride Amastatin hydrate hydrochloride L-Aspartic acid,N-[(2S,3R)-3-amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl-L-valyl-,monohydrochloride (9CI) 4-formylphenyl-O-β-d-allopyranoside AMASTATIN HCL AMASTATIN 100938-10-1 C21H38N4O8HCl C21H38N4O8HClxH2O C21H38N4O8ClH BioChemical Antibiotics Antibiotics A to Z Antibiotics A-F peptides inhibitor Pepetides