L-Homoserine
- CAS No.
- 672-15-1
- Chemical Name:
- L-Homoserine
- Synonyms
- HOMOSERINE;HSE;(S)-2-AMINO-4-HYDROXYBUTANOIC ACID;H-HOMOSER-OH;H-HSE-OH;H-HOSER-OH;H-HOMOSERINE;(2S)-2-Amino-4-hydroxybutanoic acid;RODH;SDR9C6
- CBNumber:
- CB2854094
- Molecular Formula:
- C4H9NO3
- Molecular Weight:
- 119.12
- MOL File:
- 672-15-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/13 18:16:27
Melting point | 203 °C (dec.)(lit.) |
---|---|
Boiling point | 222.38°C (rough estimate) |
alpha | -8.5 º (c=2, H2O 22 ºC) |
Density | 1.3126 (rough estimate) |
refractive index | 1.4183 (estimate) |
storage temp. | Store below +30°C. |
solubility | 1100g/l |
form | Crystalline Powder |
pka | 2.71(at 25℃) |
color | White to light yellow |
Water Solubility | 1100 g/L (30 ºC) |
Merck | 14,4739 |
BRN | 1721681 |
InChIKey | UKAUYVFTDYCKQA-VKHMYHEASA-N |
LogP | -1.289 (est) |
CAS DataBase Reference | 672-15-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P271-P280 | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 24/25-44-35-26-28-7-4-3/9 | |||||||||
WGK Germany | 3 | |||||||||
F | 10 | |||||||||
HS Code | 29225000 | |||||||||
NFPA 704 |
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L-Homoserine price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | H6515 | L-Homoserine | 672-15-1 | 10MG | ₹1905.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H6515 | L-Homoserine | 672-15-1 | 250MG | ₹10879.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H6515 | L-Homoserine | 672-15-1 | 1G | ₹20675.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H6515 | L-Homoserine | 672-15-1 | 5G | ₹74421.88 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.14359 | L-(-)-Homoserine for synthesis | 672-15-1 | 1G | ₹7360 | 2022-06-14 | Buy |
L-Homoserine Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystalline powder
Uses
L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine. It is also used as an internal standard for neurotransmitter analysis and amino acids quantification.
Definition
ChEBI: L-homoserine is the L-enantiomer of homoserine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is an enantiomer of a D-homoserine. It is a tautomer of a L-homoserine zwitterion.
General Description
L-Homoserine is a variant of serine with an additional carbon on its side chain.
Biochem/physiol Actions
L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.
Purification Methods
Likely impurities are N-chloroacetyl-L-homoserine, N-chloroacetyl-D-homoserine, L-homoserine, homoserine lactone, homoserine anhydride (formed in strong solutions of homoserine if slightly acidic). It cyclises to the lactone in strongly acidic solution. It crystallises from water by adding 9 volumes of EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2612-2616 1961, Beilstein 4 IV 3187.]
L-Homoserine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
Sami Sabinsa Group Limited (formerly Sami Labs Limited) | +91-8028397978 +91-9972587319 | Karnataka, India | 66 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Bharavi Laboratories (P) Ltd. | 91 80 2666 7742 | New Delhi, India | 359 | 54 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
Bharavi Laboratories (P) Ltd. | +91 (80) 2666-1974 | New Delhi, India | 122 | 50 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | China | 888 | 58 | Inquiry |
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