L-Threonine
- CAS No.
- 72-19-5
- Chemical Name:
- L-Threonine
- Synonyms
- THREONINE;THR;H-THR-OH;Threonin;2-AMINO-3-HYDROXYBUTANOIC ACID;l-threonin;(2S,3R)-2-Amino-3-hydroxybutanoic acid;THREONINE, L-;L-2-AMINO-3-HYDROXYBUTYRIC ACID;L-A-AMINO-B-HYDROXYBUTYRIC ACID
- CBNumber:
- CB5702648
- Molecular Formula:
- C4H9NO3
- Molecular Weight:
- 119.12
- MOL File:
- 72-19-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/6 17:20:39
| Melting point | 256 °C (dec.) (lit.) |
|---|---|
| Boiling point | 222.38°C (rough estimate) |
| alpha | -28.4 º (c=6, H2O) |
| Density | 1.3126 (rough estimate) |
| FEMA | 4710 | L-THREONINE |
| refractive index | -28 ° (C=6, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| pka | 2.09(at 25℃) |
| color | Yellow |
| PH | 5-6 (100g/l, H2O, 20℃) |
| Odor | ADM L-Threonine is a high quality product specifically designed for the feed industry. Produced from advanced technology, ADM L-Threonine is composed of 100% isomerically pure L-Threonine, which translates into 100% bioavailability for swine, poultry, and other animals.mild savory |
| Odor Type | savory |
| optical activity | [α]20/D 28.5±0.5°, c = 5% in H2O |
| Water Solubility | 90 g/L (20 ºC) |
| JECFA Number | 2119 |
| Merck | 14,9380 |
| BRN | 1721646 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | AYFVYJQAPQTCCC-GBXIJSLDSA-N |
| LogP | -2.94 |
| CAS DataBase Reference | 72-19-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Threonine(72-19-5) |
| EPA Substance Registry System | L-Threonine (72-19-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XO8590000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29225000 | |||||||||
| NFPA 704 |
|
L-Threonine price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T8625 | L-Threonine reagent grade, ≥98% (HPLC) | 72-19-5 | 10G | ₹2100.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8625 | L-Threonine reagent grade, ≥98% (HPLC) | 72-19-5 | 1G | ₹2165 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8625 | L-Threonine reagent grade, ≥98% (HPLC) | 72-19-5 | 25G | ₹4070.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8625 | L-Threonine reagent grade, ≥98% (HPLC) | 72-19-5 | 100G | ₹9959 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8625 | L-Threonine reagent grade, ≥98% (HPLC) | 72-19-5 | 500G | ₹39706.1 | 2022-06-14 | Buy |
L-Threonine Chemical Properties,Uses,Production
Chemical Properties
A white or almost white, crystalline powder or colourless crystals.
Uses
L-Threonine is used to alleviate anxiety and mild depression. It is an important component of many proteins such as tooth enamel, collagen, and elastin. It is an important amino acid in the nervous system and plays a vital role in porphyrin and fat metabolism. It is useful in intestinal disorders and indigestion. It is also used as a prodrug to reliably elevate brain glycine levels.
Definition
ChEBI: An optically active form of threonine having L-configuration.
Safety Profile
Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Likely impurities are allo-threonine and glycine. Crystallise L-threonine from H2O by adding 4volumes of EtOH. Dry and store it in a desiccator. It also crystallises from 80% EtOH to give hexagonal plates m 262-263o(dec). It sublimes at 200-226o/0.3mm with 99.6% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Elliot J Chem Soc 62 1950, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 1 pp 176-183, Vol 3 pp 2238-2257 1961, Beilstein 4 IV 3171.]
L-Threonine Preparation Products And Raw materials
Raw materials
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Global( 782)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| AMINO ORGANICS | +919866989891 | Hyderabad, India | 275 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Suprim Chemicals | +91-9324311273 +91-9029752732 | Maharashtra, India | 4 | 58 | Inquiry |
| HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
| Meteoric Biopharmaceuticals Pvt. Ltd. | +91-8511121361 +91-8511121361 | Mumbai, India | 71 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
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- L-threonine is an organic substance, the chemical formula is C4H9NO3, and the molecular formula is NH2-CH(COOH)-CHOH-CH3.
- Jun 24，2022
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