Aprepitant-d4

Aprepitant-d4 Structure
CAS No.
1133387-60-6
Chemical Name:
Aprepitant-d4
Synonyms
Aprepitant-d4;[2H4]-Aprepitant;5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one;Aprepitant D4Q: What is Aprepitant D4 Q: What is the CAS Number of Aprepitant D4 Q: What is the storage condition of Aprepitant D4 Q: What are the applications of Aprepitant D4
CBNumber:
CB02104032
Molecular Formula:
C23H17D4F7N4O3
Molecular Weight:
538.451309512
MOL File:
1133387-60-6.mol
Modify Date:
2023/5/18 11:31:19

Aprepitant-d4 Properties

Melting point 242-244°C
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
color White to Off-White

Aprepitant-d4 Chemical Properties,Uses,Production

Uses

Aprepitant-d4 is a labeled analogue of Aprepitant (A729800), A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Aprepitant-d4 is a potential treatment for chemotherapy induced nausea and vomiting.

Aprepitant-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 35)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Simson Chemie 09967773737 Mumbai, India 34 58 Inquiry
Calidad Pharma Chemie 08433672794 Mumbai, India 38 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664 China 3635 55 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 China 6210 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 China 12582 58 Inquiry

1133387-60-6(Aprepitant-d4)Related Search:

Aprepitant-d4 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one 5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one [2H4]-Aprepitant Aprepitant D4Q: What is Aprepitant D4 Q: What is the CAS Number of Aprepitant D4 Q: What is the storage condition of Aprepitant D4 Q: What are the applications of Aprepitant D4 1133387-60-6 C23H17F7N4O3D4 Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals