Defluoro Aprepitant

Defluoro Aprepitant Structure
CAS No.
170729-76-7
Chemical Name:
Defluoro Aprepitant
Synonyms
SM001C;Deflurepitan;Desfluaripitan;Enantiomers of SRS;Aprepitant USP RC A;Defluoro Aprepitant;Aprepitant desfluoro;Aprepitant Impurity 8;Aprepitant impurity 01;Aprepitant EP Impurity A
CBNumber:
CB22543774
Molecular Formula:
C23H22F6N4O3
Molecular Weight:
516.44
MOL File:
170729-76-7.mol
MSDS File:
SDS
Modify Date:
2024/6/11 18:14:38

Defluoro Aprepitant Properties

Density 1.47±0.1 g/cm3(Predicted)
pka 8.09±0.20(Predicted)

SAFETY

Risk and Safety Statements

HS Code  2934990002

Defluoro Aprepitant Chemical Properties,Uses,Production

Uses

Defluoro Aprepitant (Aprepitant EP Impurity A) is a NK-1 receptor antagonists for treating severe anxiety disorders. Antidepressant.

Defluoro Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

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5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-phenyl-4-Morpholinyl]Methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one Aprepitant EP Impurity A Aprepitant desfluoro Desfluoro Aprepitant (5-{[(2R,3S)-2-{(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenylmorpholi (1041992) SM001C 5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenyl-4-morpholinyl]methyl]-1,2-dihydro- Desfluaripitan Enantiomers of SRS Deflurepitan Aprepitant EP Impurity A (Defluoro Aprepitant) 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-1H-1,2,4-triazol-3(2H)-one Aprepitant impurity 1/Aprepitant EP Impurity A /Defluoro Aprepitant Aprepitant USP RC A Aprepitant EP Impurity A(Desfluoro Aprepitant) Aprepitant Impurity 8(Aprepitant EP Impurity A) Aprepitant Impurity 8 Aprepitant impurity 01 Desfluoro aprepitant(5-([(2R,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-phenyl morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one) Defluoro Aprepitant 170729-76-7 C23H22F6N4O3 Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals