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Atenolol

CAS No.: 29122-68-7

Chemical Name:: Atenolol

Synonyms: (RS)-ATENOLOL;Seles;Aterol;TENORMIN;ici66082;dl-Atenolol;noten;Xaten;Unilo;Altol

CBNumber:: CB3753116

Molecular Formula:: C14H22N2O3

Molecular Weight:: 266.34

MOL File:: 29122-68-7.mol

MSDS File:: SDS

Modify Date:: 2024/7/26 15:15:06

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Atenolol Properties

Melting point	154°C
Boiling point	409.54°C (rough estimate)
Density	1.0807 (rough estimate)
refractive index	1.5110 (estimate)
Flash point	2℃
storage temp.	2-8°C
solubility	H₂O: 0.3 mg/mL
form	powder
pka	9.6(at 25℃)
color	white to off-white
Water Solubility	13.5mg/L(25 ºC)
Merck	14,859
BCS Class	3
InChIKey	METKIMKYRPQLGS-UHFFFAOYSA-N
CAS DataBase Reference	29122-68-7(CAS DataBase Reference)
NIST Chemistry Reference	Atenolol(29122-68-7)
EPA Substance Registry System	Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- (29122-68-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H302+H312+H332-H319

Precautionary statements

P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235

Hazard Codes

Xn,F

Risk Statements

22-36/37/38-20/21/22-36-11

Safety Statements

22-24/25-36-26-36/37-16

RIDADR

UN 1648 3 / PGII

WGK Germany

RTECS

AC3600000

HazardClass

IRRITANT

HS Code

29242995

Toxicity

LD50 in mice, rats (mg/kg): 2000, 3000 orally; 98.7, 59.24 i.v. (Fitzgerald)

NFPA 704

	0
2		0

Atenolol price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	A7655	Atenolol ≥98% (TLC), powder	29122-68-7	1G	₹11236.35	2022-06-14	Buy
Sigma-Aldrich(India)	A7655	Atenolol ≥98% (TLC), powder	29122-68-7	5G	₹18207.65	2022-06-14	Buy
Sigma-Aldrich(India)	PHR1909	Atenolol Pharmaceutical Secondary Standard; Certified Reference Material	29122-68-7	500MG	₹19863.88	2022-06-14	Buy
Sigma-Aldrich(India)	A7655	Atenolol ≥98% (TLC), powder	29122-68-7	25G	₹57729.73	2022-06-14	Buy
Sigma-Aldrich(India)	A-072	Atenolol solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?	29122-68-7	1ML	₹3311.7	2022-06-14	Buy

Product number	Packaging	Price	Buy
A7655	1G	₹11236.35	Buy
A7655	5G	₹18207.65	Buy
PHR1909	500MG	₹19863.88	Buy
A7655	25G	₹57729.73	Buy
A-072	1ML	₹3311.7	Buy

Atenolol Chemical Properties,Uses,Production

Chemical Properties

White or almost white powder.

Uses

Atenolol is 2-[4′[2-hydroxy-3-(iso-propylamino)propoxy]phenyl]acetamide (12.1.7) [11–13].Atenolol is a selective β1-adrenoblocker, or in other words, a cardioblocker. Like acebutol, atenolol possesses antianginal, antihypotensive, and antiarrhythmic action. It is used for arterial hypotension, preventing attacks of angina, sinus tachycardia, and preventing supraventricular tachyarrhythmia.

Definition

ChEBI: An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Biological Activity

Cardioselective β -adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic.

Metabolism

Roughly half of an orally administered dose of atenolol (Tenormin) is absorbed.The drug is eliminated primarily by the kidney and unlike propranolol, undergoes little hepatic metabolism. Its plasma half-life is approximately 6 hours, although if it is administered to a patient with impaired renal function, its half-life can be considerably prolonged.

Atenolol Preparation Products And Raw materials

Raw materials

4'-Hydroxyacetophenone Isopropylamine Epichlorohydrin 4-Hydroxyphenylacetamide

Preparation Products

(+)-4-[2-HYDROXY-3-[(1-METHYLETHYL)-AMINO]PROPOXY]BENZENEACETAMIDE 2-[4-[(2RS)-2-HYDROXY-3[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETONITRILE

Atenolol Suppliers

Global( 375)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
AVD pharmaceuticals Pvt Ltd	+919860835260	Pune, India	102	58	Inquiry
Anant Pharmaceuticals Pvt Ltd	+91-8550986868 +91-9485998001	Haryana, India	461	58	Inquiry
Frolic Pharmachem	+919711094561	Himachal Pradesh, India	94	58	Inquiry
KARPSCHEM LABORATORIES	+91-7249203006 +91-7249203006	Maharashtra, India	786	58	Inquiry
Kopran Ltd	+91-9920289074 +91-9820220525	Maharashtra, India	21	58	Inquiry
Vani Pharma Labs Limited	+91-4023193245 +91-4023193245	Hyderabad, India	17	58	Inquiry
J.B. Chemicals Pharmaceuticals Ltd.	+91-022-24822222 +91-02224822222	Mumbai, India	10	58	Inquiry
Zydus Lifesciences Ltd.	+91-0265-2315243 +91-6358895661	Gujarat, India	89	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
Sai Supreme Chemicals	+91-9884178549 +91-9884178549	Tamil Nadu, India	3	58	Inquiry

Supplier	Advantage
AVD pharmaceuticals Pvt Ltd	58
Anant Pharmaceuticals Pvt Ltd	58
Frolic Pharmachem	58
KARPSCHEM LABORATORIES	58
Kopran Ltd	58
Vani Pharma Labs Limited	58
J.B. Chemicals Pharmaceuticals Ltd.	58
Zydus Lifesciences Ltd.	58
Ralington Pharma	58
Sai Supreme Chemicals	58

Atenolol Spectrum

Atenolol(29122-68-7)MS Atenolol(29122-68-7)¹HNMR Atenolol(29122-68-7)¹³CNMR Atenolol(29122-68-7)IR1 Atenolol(29122-68-7)IR2

29122-68-7(Atenolol)Related Search:

Methoxydiethylborane p-(2-Methoxyethyl) phenol Betaine CHLOROPHOSPHONAZO III ALTRENOGEST

Glycine Thioacetamide Acetamide N,N-Dimethylacetamide 2-HYDROXYACETAMIDE

S(-)-ATENOLOL >96% ACTIVE ENANTIOMER OF,S(-)-ATENOLOL R(+)-ATENOLOL LESS ACTIVE ENANTIOME,(R)-(+)-ATENOLOL ATENOLOL IMPURITY A,ATENOLOL IMP A Propoxybenzene ATENOLOL-D7

2-[4-(2,3-EPOXYPROPOXY)PHENYL]ACETAMIDE ATENOLOL-D7 (ISO-PROPYL-D7) ATENOLOL IMPURITY B

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noten (RS)-ATENOLOL (RS)-4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]BENZENEACETAMIDE TENORMIN tenlol 1-p-carbamoylmethylphenoxy-3-isopropylamino-2-propanol 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-acetamid 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenylacetamide 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-benzeneacetamid 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetamid atehexal atenol duraatenolol ibinolo ici66082 myocord normiten prenormine selesbeta selobloc tenobloc tenormine unibloc uniloc LABOTEST-BB LT00134657 apo-atenolol (+/-)-ATENOLOL ATENOLOL anselol 2-[4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)PHENYL]ACETAMIDE (+/-)-4-(2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY)BENZENEACETAMIDE 4-[2'-HYDROXY-3'-(ISOPROPYLAMINO)-PROPOXY]PHENYLACETAMIDE Atenolol,98% ATENOLOL USP 23 Tenolol Tenoprin Tensig Tensimin Tredol Vascoten Vericordin Wesipin Xaten 4-(2-Hydroy-3-izopropylamino)propoxyphenylacetamide 4-[2μ-Hydroxy-3μ-(isopropylamino)propoxy]phenylacetamide, (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide 2-[4-[3-(Isopropylamino)-2-hydroxypropoxy]phenyl]acetamide 4-[2-Hydroxy-3-(isopropylamino)propoxy]benzeneacetamide 4-[3-(Isopropylamino)-2-hydroxypropoxy]benzeneacetamide IC-166082 2-(p-(2-hydroxy-3-(isopropylamino)prop Atenolol,(±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide Atenolol (200 mg) NorMopresil Atenolol solution 2-[4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetamide Atenolol CAS 29122-68-7 (+/-)-Atenolol ((±