(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE

CAS No.: 204067-01-6

Chemical Name:: (S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE

Synonyms: PD 176252;(2S)-3-(1H-INDOL-3-YL)-N-[[1-(5-METHOXYPYRIDIN-2-YL)CYCLOHEXYL]METHYL]-2-METHYL-2-[(4-NITROPHENYL)CARBAMOYLAMINO]PROPANAMIDE;(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE;(S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino]carbonyl]amino-1H-indole-3-propanamide;1H-Indole-3-propanamide, N-[[1-(5-methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[(4-nitrophenyl)amino]carbonyl]amino]-, (αS)-

CBNumber:: CB02453426

Molecular Formula:: C32H36N6O5

Molecular Weight:: 584.67

MOL File:: 204067-01-6.mol

Modify Date:: 2024/7/2 8:54:57

Request For Quotation

(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Properties

Boiling point	838.8±65.0 °C(Predicted)
Density	1.297±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble to 100 mM in DMSO
form	Powder
pka	11.60±0.46(Predicted)
color	Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Chemical Properties,Uses,Production

Biological Activity

Non-peptide gastrin-releasing peptide receptor (GRP-R, BB 2 ) and neuromedin B receptor (NMB-R, BB 1 ) antagonist (K i values are 0.17 and 1.0 nM for BB 1 and BB 2 respectively). Inhibits proliferation of rat C6 glioma cells (IC 50 = 2 μ M) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC 50 = 5 μ M).

(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE Suppliers

Global( 27)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Guangzhou Younan Technology Co., Ltd	020-020-82000279 18988968278	China	4297	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24647	58	Inquiry
BOC Sciences		USA	0	65	Inquiry
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	China	4738	58	Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	China	15848	69	Inquiry
Tocris Bioscience	+44 (0) 117 916 3333	United Kingdom	5729	77	Inquiry
ApexBio Technology	+ 1-832-696-8203	United States	6254	58	Inquiry
Beijing Bolide Biotechnology Co., Ltd.	010-51653916	CHINA	6172	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Guangzhou Younan Technology Co., Ltd	58
TargetMol Chemicals Inc.	58
BOC Sciences	65
Nantong QuanYi Biotechnology Co., Ltd	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Tocris Bioscience	77
ApexBio Technology	58
Beijing Bolide Biotechnology Co., Ltd.	58

204067-01-6((S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE)Related Search:

Sulfanilamide 6-Isopropylpyridin-3-ol (S)-A-METHYL-A-[[[(4-NITROPHENYL)AMINO]CARBONYL]AMINO]-N-[[1-(2-PYRIDINYL)CYCLOHEXYL]METHYL]-1H-INDOLE-3-PROPANAMIDE (S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE

(S)-N-[[1-(5-METHOXY-2-PYRIDINYL)CYCLOHEXYL]METHYL]-A-METHYL-A-[[-(4-NITROPHENYL)AMINO]CARBONYL]AMINO-1H-INDOLE-3-PROPANAMIDE PD 176252 (S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino]carbonyl]amino-1H-indole-3-propanamide (2S)-3-(1H-INDOL-3-YL)-N-[[1-(5-METHOXYPYRIDIN-2-YL)CYCLOHEXYL]METHYL]-2-METHYL-2-[(4-NITROPHENYL)CARBAMOYLAMINO]PROPANAMIDE 1H-Indole-3-propanamide, N-[[1-(5-methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[(4-nitrophenyl)amino]carbonyl]amino]-, (αS)- 204067-01-6 C32H36N6O5