ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Chloropyridine >2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Structure
CAS No.
145100-51-2
Chemical Name:
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Synonyms
Comins;N-(5-CHLORO-2-PYRIDYL)TRIFLIMIDE;N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-;N-(5-CHLORO-2-PYRIDYL)BIS(TRIFLUOROMETHANESULFONIMIDE);N,N-BIS(TRIFLUOROMETHYLSULFONYL)-5-CHLORO-2-PYRIDYLAMINE;2-[N,N-BIS(TRIFLUOROMETHYLSULPHONYL)AMINO]-5-CHLOROPYRIDINE;N-(5-Chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide;Comins'reagent;Comins Triflating Reagent;N-(5-Chloropyridin-2-yl)triflimide
CBNumber:
CB0248253
Molecular Formula:
C7H3ClF6N2O4S2
Molecular Weight:
392.68
MOL File:
145100-51-2.mol
MSDS File:
SDS
Modify Date:
2023/10/31 16:47:27

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Properties

Melting point 45-47 °C(lit.)
Boiling point 77-90°C/0.2mmHg
Density 1.892±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Benzene (Slightly)
form Solid
pka -7.71±0.10(Predicted)
color yellow
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 5833971
Stability Moisture Sensitive, Unstable in DMSO Solution
InChIKey TUFGVZMNGTYAQD-UHFFFAOYSA-N
CAS DataBase Reference 145100-51-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
9
Hazard Note  Irritant
HazardClass  AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD
HS Code  29350090
NFPA 704
1
2 1

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 403644 N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) 96% 145100-51-2 1G ₹1948.5 2022-06-14 Buy
Sigma-Aldrich(India) 403644 N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide) 96% 145100-51-2 5G ₹8497.63 2022-06-14 Buy
TCI Chemicals (India) B1865 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent] min. 96.0 % 145100-51-2 5G ₹8700 2022-05-26 Buy
TCI Chemicals (India) B1865 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent] min. 96.0 % 145100-51-2 25G ₹26800 2022-05-26 Buy
Product number Packaging Price Buy
403644 1G ₹1948.5 Buy
403644 5G ₹8497.63 Buy
B1865 5G ₹8700 Buy
B1865 25G ₹26800 Buy

2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Chemical Properties,Uses,Production

Chemical Properties

White to pale yellow crystalline solid

Uses

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.

Global( 244)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ALS INDIA LIFE SCIENCES +91-8977036379 +91-8977036379 Hyderabad, India 1879 58 Inquiry
SL Drugs and Pharmaceuticals Pvt. Ltd. +91 (40) 6661-1133 New Delhi, India 2688 50 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +8613288715578 China 12456 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 10978 58 Inquiry
Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE) 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine ,98% Comins Triflating Reagent N-(5-Chloro-2-pyridyl)triflimide N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide Comins Triflating Reagent N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoroMethane)sulfonylMethanesulfonaMide 2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine N-(5-Chloropyridin-2-yl)triflimide 2-[N,N-BIS(TRIFLUOROMETHANESULPHONYL)AMINO]-5-CHLOROPYRIDINE 2-[N,N-BIS(TRIFLUOROMETHYLSULFONYL)AMINO]-5-CHLOROPYRIDINE 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Bistrifluoromethylsulfonylaminochloropyridine Comins'reagent N-(5-chloropyridin-2-yl)trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide n-(5-chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide 2-[N,N-bis(trifluoromethylsulphony)amino]-5-chloropyridine 2-[N,N-BIS(TRIFLUROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE N-(5-chloro-2-pyridyl)bis(trifluromethanesulfonimide 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent] 2-N,N-Bis(trifluoromethanesulfonyl)aminoü-5-chloropyridine, 99% 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine[TriflatingReagent]> Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE ISO 9001:2015 REACH N-(5-CHLORO-2-PYRIDYL)BIS(TRIFLUOROMETHANESULFONIMIDE) N,N-BIS(TRIFLUOROMETHYLSULFONYL)-5-CHLORO-2-PYRIDYLAMINE Comins N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N- 2-[N,N-BIS(TRIFLUOROMETHYLSULPHONYL)AMINO]-5-CHLOROPYRIDINE N-(5-CHLORO-2-PYRIDYL)TRIFLIMIDE N-(5-Chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide N-(5-chloro-2-pyridyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide 145100-51-2 C7Cl1F6H3N2O4S2 C7H3ClF6N2O4S2 Halopyridines Chloropyridines Building Blocks C7 and C8 Heterocyclic Building Blocks Pyridines Chloropyridines Halopyridines