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INK1117

INK1117 Structure
CAS No.
1268454-23-4
Chemical Name:
INK1117
Synonyms
TAK117;MLN1117;TAK 117;TAK-117;CS-2200;SerabeL;Serabelisib;INK-1117 MLN1117;MLN1117 (INK1117);Serabelisib(INK-1117)
CBNumber:
CB02716280
Molecular Formula:
C19H17N5O3
Molecular Weight:
363.37
MOL File:
1268454-23-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:57
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INK1117 Properties

Density 1.55±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≤1mg/ml in DMSO;0.25mg/ml in dimethyl formamide
form crystalline solid
pka 4.75±0.50(Predicted)
color White to gray

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

INK1117 Chemical Properties,Uses,Production

Uses

INK1117 is an inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC50 = 15 nM for PI3Kα vs. >1 μM for other isoforms, as well as for mTOR) and in cells when used at 1 μM. It blocks signaling to Akt and inhibits growth of cancer cells harboring wild-type or mutated p110α. INK1117 does not interfere with B cell proliferation or NK cell maturation and survival.[Cayman Chemical]

INK1117 Preparation Products And Raw materials

Raw materials

Methanone, (6-?bromoimidazo[1,?2-?a]?pyridin-?3-?yl)?-?4-?morpholinyl- 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)benzo[d]oxazol-2-amine 5-BROMOBENZO[D]OXAZOL-2-AMINE 6-Bromoimidazo[1,2-a]pyridine-3-carboxylicacid (2-Aminobenzo[d]oxazol-5-yl)-boronic acid hydrochloride
IMidazo[1,2-a]pyridine-3-carboxylic acid, 6-broMo-, ethyl ester 2-Amino-4-bromophenol
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Preparation Products

INK1117 Suppliers

Global( 91)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd +86-86-22-87899925 +86-8618522618860 China 694 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58

1268454-23-4(INK1117)Related Search:

RESATORVID TAK-063 TAK-960 TAK-733 Vonoprazan fumarate
Amino alcohol 2,6-Dichlorobenzoxazole Thianaphthene 2-(P-TOLYL)BENZOXAZOLE Quinazoline
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Methanone, [6-(2-aMino-5-benzoxazolyl)iMidazo[1,2-a]pyridin-3-yl]-4-Morpholinyl- INK-1117 MLN1117 MLN1117 MLN1117 (INK1117) [6-(2-Amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinylmethanone [6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholin-4-ylmethanone methyl 6-((5-((3-(trifluoromethyl)phenyl)carbamoyl)naphthalen-2-yl)oxy)pyrimidine-4-carboxylate TAK-117(INK1117,MLN1117) Serabelisib (MLN1117) Serabelisib(INK-1117) Serabelisib Serabelisib,MLN1117,INK1117, TAK-117 Serabelisib(TAK-117,INK1117,MLN1117) INK1117; INK-1117; INK 1117; MLN1117; MLN 1117; MLN-1117; TAK-117; TAK 117; TAK117 TAK 117 TAK117 TAK-117 CS-2200 MLN1117 (Serabelisib) 5-[3-(Morpholine-4-carbonyl)imidazo[1,2-a]pyridin-6-yl]-1,3-benzoxazol-2-amine Serabelisib (TAK-117) SerabeL (6-(2-Aminobenzo[d]oxazol-5-yl)imidazo[1,2-a]pyridin-3-yl)(morpholino)methanone 1268454-23-4