RESATORVID
- CAS No.
- 243984-11-4
- Chemical Name:
- RESATORVID
- Synonyms
- CS-1150;TAK 242;Resatorvi;RESATORVID;TAK-242(Resatorvid);Resatorvid(TAK-242);RESATORVID; TAK242; TAK 242;(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate;Ethyl (R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]-1-cyclohexenecarboxylate;ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate
- CBNumber:
- CB92455670
- Molecular Formula:
- C15H17ClFNO4S
- Molecular Weight:
- 361.82
- MOL File:
- 243984-11-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:41
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
HS Code | 2935909099 | |||||||||
NFPA 704 |
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RESATORVID price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 614316 | TLR4 Inhibitor, TAK-242 - CAS 243984-11-4 - Calbiochem TAK-242; CAS 243984-11-4; is a cell-permeable compound that selectively binds to Cys747 of TLR4 and selectively disrupts its interaction with adaptor | 243984-11-4 | 5MG | ₹27080 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 5.08336 | InSolution TLR4 Inhibitor, TAK-242 - CAS 243984-11-4 - Calbiochem A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO. | 243984-11-4 | 2MG | ₹11740 | 2022-06-14 | Buy |
RESATORVID Chemical Properties,Uses,Production
General Description
A cell-permeable cyclohexenecarboxylate that disrupts TLR4, but not TLR1-3 or TLR5-10, interaction with adaptor molecules TIRAP and TRAM via direct binding to TLR4 intracellular Cys747 residue.Shown to effectively inhibit TLR4-mediated cellular events (IC50 = 1.8, 1.3, and 1.9 nM, respectively, against LPS-induced NO, IL-6, and TNF-α production in murine RAW264.7 macrophages) in vitro and completely prevent LPS- (7 mg/kg, i.p.) induced death in mice (3 mg/kg; i.v.) in vivo. Also available as a 25 mM solution in DMSO (Cat. No. 508336).
Biochem/physiol Actions
Cell permeable: yes
RESATORVID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 120)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13341 | 58 | Inquiry |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9640 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
changzhou huayang technology co., ltd | +8615250961469 | China | 9827 | 58 | Inquiry |
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TAK-242(Resatorvid)
1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)aMino]sulfonyl]-, ethyl ester, (6R)-
Resatorvid(TAK-242)
Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-, ethyl ester, (6R)-
(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate
RESATORVID
TAK 242
(6R)-6-[[(2-Chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid ethyl ester
RESATORVID; TAK242; TAK 242
CS-1150
ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate
(R)-Ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate[Resatorvid
Resatorvi
Ethyl (R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]-1-cyclohexenecarboxylate
243984-11-4
C15H17ClFNO4S
MAPK
API