레사토르비드
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레사토르비드 속성
- 녹는점
- 68-69℃
- 끓는 점
- 462.0±55.0 °C(Predicted)
- 밀도
- 1.39
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- insoluble in H2O; ≥100.6 mg/mL in EtOH; ≥18.09 mg/mL in DMSO
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 7.08±0.40(Predicted)
- 색상
- Off-white to yellow
레사토르비드 C화학적 특성, 용도, 생산
일반 설명
A cell-permeable cyclohexenecarboxylate that disrupts TLR4, but not TLR1-3 or TLR5-10, interaction with adaptor molecules TIRAP and TRAM via direct binding to TLR4 intracellular Cys747 residue.Shown to effectively inhibit TLR4-mediated cellular events (IC50 = 1.8, 1.3, and 1.9 nM, respectively, against LPS-induced NO, IL-6, and TNF-α production in murine RAW264.7 macrophages) in vitro and completely prevent LPS- (7 mg/kg, i.p.) induced death in mice (3 mg/kg; i.v.) in vivo. Also available as a 25 mM solution in DMSO (Cat. No. 508336).Biochem/physiol Actions
Cell permeable: yes레사토르비드 준비 용품 및 원자재
원자재
준비 용품
레사토르비드 공급 업체
글로벌( 120)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29892 | 58 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 13260 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9602 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9923 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
CR Corporation Lomited | |
fred.wen@crcorporation.cn | CHINA | 12069 | 58 |
레사토르비드 관련 검색:
Abiraterone acetate
D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE
Rapamycin
Celastrol
Abiraterone
340722-43-2
ethyl 2-(chlorosulfonyl)cyclohex-1-enecarboxylate
1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)aMino]sulfonyl]-, ethyl ester
2-(ethoxycarbonyl)cyclohex-1-ene-1-sulfonic acid
ethyl 2-Mercaptocyclohex-1-enecarboxylate
Ethyl 2-oxocyclohexanecarboxylate
Vonoprazan fumarate
INK1117
TAK-733
TAK-960
TAK-063
Resatorvid Impurity 6
Resatorvid Impurity 9