INK1117
INK1117
- CAS:
- 1268454-23-4
- MF:
- C19H17N5O3
- MW:
- 363.37
Suppliers by country/region
Company Type
Properties
- Density
- 1.55±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≤1mg/ml in DMSO;0.25mg/ml in dimethyl formamide
- form
- crystalline solid
- pka
- 4.75±0.50(Predicted)
- color
- White to gray
Safety Information
Use
INK1117 is an inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC50 = 15 nM for PI3Kα vs. >1 μM for other isoforms, as well as for mTOR) and in cells when used at 1 μM. It blocks signaling to Akt and inhibits growth of cancer cells harboring wild-type or mutated p110α. INK1117 does not interfere with B cell proliferation or NK cell maturation and survival.[Cayman Chemical]
0 India supplier list of "INK1117"